depressive disorders

SSRI/SNRI common suffixes

-ine/alopram/pran/oxetine

how long do SSRIs and MAOIs take to see effects? how long to see full effects?

1-3 weeks; 2-3 months

SSRI adverse effects (10)

sexual dysfunction, CNS stimulation, NMS, suicidal thoughts, weight loss, serotonin syndrome, hyponatremia, rash, GI bleeding, and bruxism

serotonin syndrome can begin how long after starting SSRI treatment and can be ______

2-72 hrs; lethal

are SSRIs pregnancy-safe?

no

SNRIs adverse effects (6)

adrenergic effects, NMS, HA, suicidal, sexual dysfunction, and serotonin syndrome

are SNRIs pregnancy-safe?

no

atypical antidepressant prototype

buspirone

atypical antidepressants common suffixes

-azodone/zapine

atypical antidepressants adverse effects (3)

adrenergic effects, weight loss, and seizures

what are atypical antidepressants especially contraindicated in?

lactation

tricyclic antidepressant prototype

amitriptyline

tricyclic antidepressants common suffixes

-triptyline/ipramine

tricyclic antidepressants complications beginning with the most serious (5)

decreased seizure threshold, orthostatic hypotension, adrenergic effects, sedation, and sweating

tricyclic antidepressants have a risk of _________, so monitor which patients heavily and give meds to them how often?

lethality; suicidal; 1 week at a time

MAOI prototype

phenelzine

transdermal MAOI

selegilline

MAOI adverse effects (3)

CNS stimulation, orthostatic hypotension, and HTN crisis

safety of MAOIs is not established for those who are…

lactating

obtain baseline ______ levels in older adults taking diuretics using SSRIs/SNRIs and monitor

sodium

monitor for what in TCA patients due to risk of lethality in toxicity

cheeking