Peripheral Nervous System Drugs – Veterinary Pharmacology (VSCT 214)

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Vocabulary flashcards covering direct-acting and indirect-acting cholinergics, anticholinergics, adrenergic agents (natural and synthetic), and adrenergic antagonists as listed in the lecture notes.

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21 Terms

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Bethanechol

Direct-acting cholinergic that stimulates muscarinic receptors; helps with bladder and GI emptying.

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Pilocarpine

Direct-acting cholinergic that reduces intraocular pressure.

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Metoclopramide (Reglan)

Direct-acting agent that controls vomiting and promotes gastric emptying.

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Edrophonium (Tensilon)

Indirect-acting cholinergic used to diagnose myasthenia gravis.

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Neostigmine

Indirect-acting cholinergic; helps promote GI and bladder emptying; used to treat rumen and intestinal atony.

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Physostigmine

Indirect-acting cholinergic; helps promote GI and bladder emptying; used to treat rumen and intestinal atony.

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Pyridostigmine

Indirect-acting cholinergic; treatment of myasthenia gravis.

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Atropine

Anticholinergic: Topical ophthalmic dilates pupils for exam or ocular pain relief; Injectable prevents/bradycardia with anesthesia, treats bradycardia, slows gut motility.

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Glycopyrrolate

Anticholinergic similar to atropine but more potent with longer duration; often used in preanesthetic.

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Pralidoxime

Anticholinergic that treats organophosphate toxicity by reactivating acetylcholinesterase.

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Epinephrine

Natural adrenergic drug; nonselective stimulation of receptors to increase heart rate, cardiac output, and metabolism.

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Norepinephrine

Natural adrenergic drug that stimulates sympathetic receptors.

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Dopamine

Precursor to epinephrine and norepinephrine; treats shock, heart failure; increases renal perfusion.

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Phenylephrine

Synthetic adrenergic drug; alpha-adrenergic stimulator and nasal vasoconstrictor.

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Phenylpropanolamine (Proin)

Synthetic adrenergic drug; treats urinary incontinence in dogs.

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Dobutamine

Synthetic adrenergic drug; beta-1 stimulator; short-term treatment of heart failure.

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Albuterol

Synthetic adrenergic drug; beta stimulator; bronchodilator.

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Acepromazine

Alpha-receptor blocking drug; tranquilizer that causes vasodilation.

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Prazosin

Alpha-receptor blocking drug; hypotensive agent used for urethral spasm in cats.

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Yohimbine

Alpha-receptor blocking drug; antidote for xylazine.

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Atipamezole (Antisedan)

Alpha-receptor blocking drug; reversal agent for dexmedetomidine (Dexdomitor).