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Metabolism: Energy and Enzymes
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metabolism
the sum of all the chemical reactions that occur in a cell
catabolism
the breaking down of molecules
anabolism
the building up (synthesis) of molecules
reactants
in a chemical reaction, the substances that participate in a reaction
products
in a chemical reaction, the substances that form as a result of a reaction
free energy
the amount of energy available after a chemical reaction as occurred; also called ΔG
exergonic reactions
reactions that are spontaneous and release energy
endergonic reactions
reactions that require an input of energy to occur
ATP (adenosine triphosphate)
the common energy currency of cells; supplies energy for chemical work, transport work, and mechanical work by being converted to ADP plus a phosphate group
ADP (adenosine diphosphate)
a nucleotide that can accept another phosphate group and become ATP
metabolic pathway
a series of linked reactions that begin with a particular reactant and terminate with an end product
enzymes
types of proteins that function as catalysts to speed up chemical reactions
substrates
reactants in an enzymatic reaction
energy of activation (Ea)
the energy that must be added to cause molecules to react with one another
active site
a small part of an enzyme that forms a complex with a substrate(s)
induced fit model
when the enzyme undergoes a slight change in shape in order to accommodate the substrate
denatured
describes a protein that has had an irreversible change in its shape; occurs when proteins are exposed to extremes in heat and pH
enzyme inhibition
occurs when the substrate is unable to bind to the active site of an enzyme
cofactors
inorganic ion helpers required by enzymes to function properly
coenzymes
organic, nonprotein molecule helpers required by enzymes to function properly
vitamins
relatively small organic molecules that are required in trace amounts in diets for synthesis of coenzymes that affect health and physical fitness
thyroid gland
a large gland in the neck that produces several important hormones, including triiodothyronine, thyroxine, and calcitonin
parathyroid glands
glands embedded behind the thyroid gland; produce parathyroid hormones
thyroxine (T4)
a hormone produced by the thyroid gland that increases metabolic rate
triiodothyronine (T3)
a hormone produced by the thyroid gland that increases metabolic rate
calcitonin
a hormone produced by the thyroid gland that helps control blood calcium levels
parathyroid glands
glands embedded behind the thyroid gland; produce parathyroid hormones
parathyroid hormone (PTH)
hormone produced by the parathyroid glands; causes the blood phosphate level to decrease and the blood calcium level to increase