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What are the coronary arteries and why are they important
The right and left coronary arteries supply oxygenated blood to the heart muscle. they perfuse during diastole, and blockage here can cause ischemia
How do arteriosclerosis and atherosclerosis lead to ischemic heart disease (IHD)
Arteriosclerosis- causes stiffening and thickening of arterial walls
Atherosclerosis- a form of arteriosclerosis, involves plaque build-up that narrows coronary arteries, reducing blood flow to the myocardium
What happens during ischemic heart disease
The myocardium (heart muscle) is deprived of oxygen due to reduced blood flow through the coronary arteries, leading to angina or myocardial infaraction
What risk factors for cardiovascular disease are modifiable and nonmodifiable
Modifiable: obesity, physical inactivity, poor diet, smoking, diabetes, hypertension
Nonmodifiable: age, gender, race/ethnicity, family history
What is angina pectoris and what causes it
Angina pectoris is squeezing chest pain from temporary myocardial ischemia (low oxygen). it can radiate to the neck, jaw, upper abdomen, or arms
What are other common symptoms of angina
Dyspnea (shortness of breath), diaphoresis (sweating), pallor, and weakness
What characterizes stable angina
Predictable chest pain that occurs with activity or stress and resolves with rest or medication (e.g., nitroglycerin)
What characterizes unstable angina?
Sudden, more severe chest pain that changes from usual patterns, does not improve with rest or medication, and is a medical emergency
What causes myocardial infarction (MI)
A complete occlusion of a coronary artery, causing irreversible myocardial damage and tissue death
What are classic signs and symptoms of MI
Crushing substernal chest pain radiating to the shoulder, arm, jaw, or back, dyspnea, diaphoresis, pallor, and elevated cardiac biomarkers (like troponin)
What electrical changes might be seen on an ECG during MI
ST-segment elevation, T-wave inversion, or Q-wave formation depending on the infarct type
What are possible complications of an MI
Dysrhythmias (abnormal rhythms)
Papillary muscle rupture (causing valve dysfunction)
Thromboembolism
Ventricular aneurysm
Pericarditis
Heart failure
Cardiogenic shock
What is infective endocarditis
A bacterial or fungal infection of the endocardium that damages heart valves and increases risk for emboli. The structure most affected in infective endocarditis are cardiac valves
What is pericarditis and what are its effects
Inflammation of the pericardium that may cause pericardial effusion, restricted heart wall motion, and possibly cardiac tamponade (compression of the heart)