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The aim of chromatography is to…
separate a mixture into its constituents
In this case the constituents are…
biological molecules
2 key phases:
stationary and mobile
Stationary phase:
chromatography paper or TLC plate
In the stationary phase there is free…
OH- groups pointing outwards, in contact with mobile phase
Mobile phase:
solvent
The solvent is water for…
polar molecules
The solvent is ethanol for…
non polar molecules
The mobile phase flows…
carrying… with it
through and across the stationary phase, carrying biological molecules with it
The distance moved by the constituents is based on their… and how well they…
size, how well they dissolve in solvent