Excipients

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49 Terms

1
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Cellulose derivatives

Bulking agent

2
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Carboxymethylcellulose sodium

Bulking agent, suspending agent, and tablet binder

3
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Acacia

Emulsifying agent and tablet binder

4
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Glyceryl Monostearate

Oleaginous fats; emulsifying agent

5
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Sorbitan Monooleate

Oleaginous fats; emulsifying agent

6
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Magnesium Stearate

Oleaginous fats; emulsifying agent and glidant

7
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Talc

Gliding agent; hydrated magnesium silicate

8
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Colloidal silicone dioxide

Glidant; adsorbant (holds molecules together and keeps dry)

9
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Crospovidone

Disintegrant; Hygroscopic (attracts water, swells, then explodes)

10
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Glycerin

Humectant, sweetener, levigating

11
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Propylene glycol

Humectant (keeps things moist)

12
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Sorbitol

Humectant, sweetener

13
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Pregelatinized starch

Tablet binder

14
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Methyl and ethyl cellulose

Tablet binder and bulking agent

15
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Povidone (PVP — polyvinylpyrrolidone)

Tablet binder

16
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Liquid glucose

Tablet binder

17
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Parabens

Antifungal

18
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Sodium Metabisulfite

Antioxidant

19
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Mineral oil

Levigating agent

20
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Alcohol

Solvent

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Vegetable and nut oil

Solvent

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Oleic acid

Solvent

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Water and saline

Solvent

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Cetyl alcohol

Stiffening/Thickening agent

25
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Cetyl esters wax

Stiffening/Thickening agent

26
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Microcrystalline wax

Stiffening/Thickening agent

27
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Lanolins

Paraffin, yellow and white wax; Stiffening/Thickening agent

28
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Clays

Agar, bentonite, kaolin; Suspending agent

29
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Carbomer

Suspending agent

30
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Hydroxyethyl, Hydroxypropyl cellulose

Suspending agent and bulking

31
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Gum

Tragacanth, Veegum; Suspending agent

32
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Aspartame

Sweetener; NutraSweet

33
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Xylitol

Sweetener; deadly for dogs — seizures, low blood sugar, liver failure

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Dextrose

Sweetener

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Mannitol

Sweetener

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Sucrose

Sweetener

37
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Saccharin sodium

Sweetener

38
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Ferric oxide derivate

Colorants

39
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Defoamer

HLB 1-3; no dispersion

40
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W/O emulsifier

HLB 3-6; poor dispersion

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Wetting agent

HLB 7-8; milky dispersion when shook

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O/W emulsifier

HLB 9-10; milky dispersion

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Detergent

HLB 11-13; opaque

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Solubilizer

HLB 14-16; clear

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Levigation

Break up particles via spatulation; begins solubilization by wetting powder

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Humectants

Keep things moist

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Glidants

Reduce friction

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Tablet binders

Make drug and inactive granules stick together

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Suspending agents

Increase viscosity and reduce sedimentation