ASCP - BB & Transfusion

AABB testing recommendation for Chagas disease

Donor has to be tested once for antibodies to Trypanosoma cruzi.

Ixodes scapularis transmits which 7 organisms

Borrelia burgdorferi / B. mayonii (Lyme)

Anaplasma phagocytophilum (anaplasmosis)

B. miyamotoi (relapsing fever)

Ehrlichia muris eauclairensis (ehrlichiosis)

Babesia microti (babesiosis)

Powassan virus (Powassan virus disease)

The Lone star tick (Amblyomma americanum) transmits which 5 organisms/diseases

Ehrlichia chaffeensis / Ehrlichia ewingii (human ehrlichiosis)

Heartland virus

Tularemia

STARI (southern-tick-associated rash illness)

Dermacentor variabilis (American dog tick / wood tick) transmits which two diseases

Tularemia

Rocky Mountain spotted fever

Rhipicephalus sanguineus (Brown dog tick) transmits which disease

Rocky Mountain spotted fever

What do the red cells demonstrate in this KB acid elution test?

Hemoglobin F

Cryoprecipitate is a source of which concentrated factors?

Fibrinogen

Factor VIII

vWF

Most common organism implicated in platelet microbial contamination

Staphylococcus spp

What morphology do Rh null RBCs exhibit

Stomatocyte

Best test and independent predictor of increased perioperative morbidity and mortality

Pre-operative Hgb

Which family of RBC antigens have disulfide bonds and will not be detected if specimen is pretreated with DTT

Kell

This RBC sample shows which process?

Hemolysis

(True / False) Hypotonic fluids can be administered at the same time as an RBC transfusion

False - it would cause acute hemolysis

Which of the Rh family antigens is easiest to find antigen-negative blood for a patient with an alloantibody in their serum

E - 71% donor RBC expected to be negative (99% of Rh neg units)

Donor form: “Since the beginning of 1980, have you ever lived in or traveled to Europe?” What was the purpose of this question?

To identify donors at risk for exposure to bovine spongiform encephalopathy (BSE)

(True / False) Granulocytes can be leukoreduced

False - inactivate basically all the cells

According to AABB standards, ABO group confirmation is required for which three blood products?

Whole blood

RBC

Granulocytes

(True / False) Rh negative blood products need Rh status confirmation

True