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What two categories of users progress to dependence
Chronic and increasing users
Withdrawal symptoms of marijuana
Irritability, increase anxiety and depression
Increase in sleep disturbances, decrease appetite
How does tolerance work with marijuana
Involves desensitization of CB1 receptors and it is coupled with down regulation of receptors
What happens with chronic exposure of marijuana
hippocampus changes
Early heavy cannabis use correlates to psychosis dependence however this may be b/c people who are likely have psychosis use cannabis
Health effects with cannabis
no repeated overdose deaths
lung damage
averse immune effects
pregnancy can be dangerous to fetus
THC has been found to decrease cognitive health