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Outline the three parts of the cell theory
All cells come from pre-existing cells
Cells are the smallest unit/building blocks of life
All organisms are composed of one or more cells
Give examples that are exceptions to the cell theory
Striated muscle cells, multiple nuclei, long fibers
Giant algae, can grow up to 100mm, unicellular, size would usually require multiple small cells
Aseptate fungal hyphae, sometimes not divided into individual cells
Viruses
Outline uses of stem cells
Unspecialized stem cells can divide
Stem cells come from embryos, bone marrow, umbilical cord blood, adult tissue
Stem cells can regenerate, repair diseased, damaged tissues in people
List the functions of life
Nutrition
Metabolism
Growth
Response
Excretion
Homeostasis
Reproduction
What are the characteristics of eukaryotic cells?
Large
Complex
Unicellular or multicellular
Has a nucleus
Has membrane bound organelles
80s ribosomes
Cell membrane
Cytoplasm
Ribosomes
DNA
What are the characteristics of prokaryotic cells?
Small
Simple
Unicellular
Has a nucleoid, no nucleus
Circular DNA (plasmids)
No membrane-bound organelles
Pilli
70s ribosomes
Outline the evidence of endosymbiotic theory
Mitochondria and chloroplasts show features common with prokaryotes
Have their own DNA
Surrounded by a double membrane
What cell organelle/component arose first during cell formation?
Cell membrane
Describe Louis Pasteur’s experiment
Had two flasks filled with nutrient broth, both had a cap with a long tube, one was boiled and didn’t have bacterial growth and the un-boiled one did, disproving the theory of spontaneous generation and proved that cells come from pre-existing cells
Compare and contrast the structure of sinusoids and capillaries
Compare: Both have walls 1 cell thick
Contrast: Sinusoids have holes
Outline how materials from red blood cells are recycled by the liver
Erythrocytes have a lifespan of approximately 120 days
Erythrocytes taken in by phagocytosis by Kupffer cells
Hemoglobin splits into globin and heme groups
Iron recycled
Heme without iron becomes bilirubin
Globin digested into amino acids
What’s the scientific name for red blood cells?
Erythrocytes
Outline the causes and consequences of jaundice
Causes:
Hepatitis
Liver cancer
Cirrhosis
Parasite infection
Excess production of bilirubin
Blocked ducts
Gall stones
Consquences
Yellowing of skin and whites of eyes
Dark urine
Grey feces
Brain damage in infants
Explain the function of hepatocytes in protein metabolism
Hepatocytes produce plasma proteins
Plasma proteins are modified by Golgi apparatus
Protein in then broken down into amino acids
Outline the circulation of blood to and from the liver
Receives oxygenated blood by the hepatic artery, used to sustain liver cells
Receives nutrient rich blood from the gut (gastrointestinal tract) via the portal vein
Deoxygenated blood is transported from the liver via the hepatic vein
What is the scientific term for liver cells?
Hepatocytes
Outline the functions of the liver
Stores and releases key nutrients such as glycogen, cholesterol and triglycerides
Detoxifies potentially harmful ingested substances such as drugs, alcohol, bacteria
Produces plasma proteins that function to maintain sustainable osmotic (water balance) conditions within the blood stream
Breakdowns red blood cells and produces bile salts
What is the endosymbiotic theory?
2 billion years ago a bacterial cell was engulfed by a eukaryote
Eukaryotes and prokaryotes have a symbiotic relationship
Bacterial cell that was in the eukaryote eventually became a mitochondria/chloroplast
Outline the function of sinusoids
Hepatocytes remove and add substances
Site of exchanges between blood and hepatocytes
Kupffer cells break down hemoglobin in red blood cells
Wall is made up of hepatocytes