organic 2 exam 1

what happens when you treat an internal alkene with O3?

an ozonolysis cleavage will occur

you will end with two aldehydes if the carbons are sp2 hybridized

what happens when you treat a terminal alkene with O3?

an ozonolysis cleavage will occur

you will end with an aldehyde and a formaldehyde

what does ozonlysis in alkenes essentially do?

replace your double bond on each carbon to a double bond to oxygen! substituents stay the same.

what happens when you add HIO4 in H2O to a 1,2 diol?

it cleaves the diol in half and creates two aldehydes if no other substituents

how can you make a terminal aldehyde?

you can do hydroboration oxidation on a terminal alkyne!

how do we make cis diols from alkenes?

we can add OsO4 in pyrimidine in NaHSO3 and H2O

what is needed to take an aldehyde / ketone to an alcohol?

1) H^- (source is NaBH4)

2) H₂O

on a board show the mechanism for how a ketone can turn into an alcohol!

okay

what is another set of conditions you can use for the reaction that turns a ketone/aldehyde into an alcohol

1. LiAlH₄ (LAH)

2. H2O