Kreb's Cycle

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21 Terms

1
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Step 1

Acetyl CoA + Oxaloacetate → Citrate

2
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What Enzyme Catalyzes Step 1?

Citrate synthase

3
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Step 2

Citrate → Isocitrate

4
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What Enzyme Catalyzes Step 2?

Aconitase

5
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Step 3

Isocitrate → Alpha ketoglutarate

6
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What Enzyme Catalyzes Step 3?

Isocitrate dehydrogenase

7
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What are the Products of Step 3?

  • NADH (NAD+ → NADH)

  • CO2

8
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Step 4

Alpha-ketoglutarate → succinylCoA

  • Most similar to the PDC

9
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What Enzyme Catalyzes Step 4?

Alpha-ketoglutarate dehydrogenase

10
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What are the Products of Step 4?

  • NADH (NAD+ → NADH)

  • CO2

11
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Step 5

SuccinylCoA → Succinate

12
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What Enzyme Catalyzes Step 5?

Succinyl-CoA synthetase

13
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What are the Products of Step 5?

  • GTP

14
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Step 6

Succinate → Fumarate

15
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What Enzyme Catalyzes Step 6?

Succinate dehydrogenase (flavoprotein)

16
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What are the Products of Step 6?

  • FADH2 (FAD → FADH2)

17
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Step 7

Fumurate → L-malate

18
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What Enzyme Catalyzes Step 7?

Fumarase

19
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Step 8

L-malate → oxaloacetate

20
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What Enzyme Catalyzes Step 8?

L-malate dehydrogenase

21
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What are the Products of Step 8?

  • NADH (NAD+ → NADH)