Pharmacy Practice 1-5 Lab Values

Sodium Function

Used for hydration status

An electrolyte

Potassium Function

Regulation of nerve impulses, muscle contraction, acid base status

An electrolyte

Chloride Function

Hydration status, acid base status

An electrolyte

Bicarbonate Function

Acid-base status

Creatinine Function

Kidney function

Used for medication dosage

Blood Urea Nitrogen Function

Kidney function

Glucose Function

Blood sugar

Calcium Function

Cellular function, parathyroid glands, bones

Estimated Glomerular Filtration Rate (EGFR) Function

Filtration rate of kidney

Used for medication dosage

Anion gap Function

Electrolyte status and acid-base imbalance

Alkaline Phosphatase (ALP) Function

Liver enzyme

Differentiates hepatobiliary disease & osteogenic bone diseas

Aspartame Aminotransferase Function

Liver enzyme

Detects hepatocellular damage to liver

Less significant than ALT

Alanine aminotransferase Function

Liver enzyme

Specific

Biirubin Function

Liver enzyme

Breakdown product of hemoglobin in RBCs

High amounts causes jaundice

Total protein Function

Albumin + globulin = total protein

Measures liver+kidney function

Albumin Function

Liver enzyme

C-reactive Protein Function

Acute phase reactant

Indicates inflammation

Acute phase reactant

Blood markers that vary by 25% due to inflammation, infection, or injury

Creatine Kinase (CK) Function

Higher in cardiac / skeletal muscle diseases

CKMB Function

Isoenzyme of creatine kinase

High levels indicate minor myocardial infarction (heart attack)

Troponin 1 (cTNI) Funcition

Specific indicator of myocardial infarction (Heart attack)

Amylase Function

Pancreatic enzyme

High levels suggest disorder

Lipase Function

Pancreatic enzyme

High levels indicate disorders

More specific than amylase

Human Chorionic Gonadotropin (hCG) Function

Hormone made by placenta

High levels indicate pregnancy

Thyroid Simulating Hormone (TSH) Function

Thyroid function

Low levels cause secretion to increase hormone production

Triiodothyronine (T3) Function

Thyroid Function

Most active thyroid function

High/Low levels indicate thyroid conditions

Thyroxine (T4) Function

Thyroid Function

What is the most active thyroid hormone?

T3

Which is the most specific pancreatic enzyme?

Lipase

What is used as a specific marker for a myocardial infarction?

Troponin 1

Total protein is a combination of

Albumin + Globulin

Which is the most specific liver enzyme?

ALT (Alanine aminotransferase)

Which two are used to create medication dosages?

Creatinine + eGFR

Which are used for acid-base status?

1. Potassium

2. Chloride

3. Bicarbonate

Normal Sodium Levels

136-145 mmol/L

Normal Potassium Levels

3.5-5.1 mmol/L

Normal Chloride Levels

98-107 mmol/L

Normal Bicarbonate Levels

22-33 mmol/L

Normal Creatinine Levels

0.8-1.2 mg/dL

Normal Blood Urea Nitrogen Levels

6-20 mg/dL

Normal Glucose Levels

74-100 mg/dL

Normal Calcium Levels

8.6-10 mg/dL

Normal eGFR levels

>60 mL/min/m²

Normal Anion gap levels

7-16 mmol/L

Normal ALP Levels

Hint: Varies for men and women.

Male: 53-128 U/L

Female: 42-98 U/L

Normal AST Levels

5-35 U/L

Normal ALT Levels

7-45 U/L

Normal Biirubin levels

0.2-1.0 mg/dL

Normal Total Protein Levels

6.5-8.3 g/dL

Normal Albumin Levels

3.5-5.4 g/dL

Normal CRP Levels

<10 mg/L

Normal CK Levels

Male: 42-98 U/L

Female: 34-145 U/L

Normal CKMB Levels

< 5% total CK

Normal Troponin 1 Levels

< 0.04 ng/mL

Normal Amylase Levels

30-220 U/L

Normal Lipase Levels

< 38 U/L

Normal hCG Levels

< 4.0 IU/L

Normal TSH Levels

0.6 - 3.3 mIU/mL

Normal T3 Levels

80-200 ng/dL

Normal T4 Levels

0.4-4.0 mIU/L

Which values have different acceptable ranges for men and women?

Alkaline Phosphatase and Creatine Kinase

Which of the following values has an acceptable range based off another value?

CKMB

Complete Metabolic Panel (CMP)

Metabolic Panel (BMP) + Liver Function Tests (LFP)