Part 9: Lipid-soluble Hormones (Steroid Hormones & Thyroid Hormones)

Lipid-soluble hormones are small, nonpolar, ________ (lipid-loving) molecules

lipophilic

Plasma membrane of a cell of a lipid-soluble hormone is not an effective _______

barrier

Unbound lipid-soluble hormones are able to ________ into the cell

diffuse

Once a lipid-soluble hormone is in the cell, the hormone binds to intracellular receptors in the cytosol or nucleus to form a ____________

hormone-receptor-complex

The hormone-receptor-complex binds to a particular DNA sequence called …….

hormone-response-complex

Binding to a hormone-response-complex results in transcription of _____ ______ ___ (mRNA)

messenger ribonucleic acid

Subsequent translation of the mRNA by ribosomes _________ a specific protein

synthesizes

The change in protein synthesis within the cell may result in…..

an alteration in cell structure

shift in target cells’ metabolic activity