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IgG
Structure: monomer
Most abundant immunoglobin
Found in blood, lymph, intestine
Enhances phagocytosis, neutralizes toxins/viruses, protects fetus and newborn
IgM
Structure: pentamer
First one produced in an infection
Found in blood, lymph, B cell surface
Especially effective against microorganisms and agglutinating antigens
IgA
Structure: dimer
Found in secretions, saliva, mucous, intestine
Localized protection on mucosal services
IgD
Structure: monomer
Found in B cell surface, blood, lymph
Serum function not known
IgE
Structure: monomer
Found in bound to mast and basophil cells throughout body, blood
Allergic reactions; possibly lysis of parasite worms