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What is the primary function of leukocytes?
Defend the body against bacteria, fungi, viruses, and parasites, and protect the body against trauma or damage, including abnormal cells.
What are the two main groups of leukocytes based on granule development?
Granulocytes (contain granules) and Agranulocytes (few or no granules).
Name the types of granulocytes.
Neutrophils, Eosinophils, and Basophils.
What types of leukocytes fall under Agranulocytes?
Lymphocytes and Monocytes.
What is the process of producing leukocytes called?
Leukopoiesis.
What is a myeloblast?
A large progenitor cell with a large nucleus, prominent nucleoli, and light to medium blue cytoplasm without visible granules.
What characterizes a promyelocyte?
Slightly larger cell with small reddish-purple granules in the cytoplasm and a round to oval nucleus.
What is the appearance of a myelocyte?
Smaller cells with few specific granules, a denser and smaller nucleus, and absent nucleoli.
What is the shape of the nucleus in a metamyleocyte?
Kidney-bean shaped, with less blue cytoplasm and possibly more specific granules.
What distinguishes a band cell from a segmented granulocyte?
A band cell has a curved or rod-shaped nucleus, while a segmented granulocyte has a lobulated nucleus.
Which leukocytes are known for having distinct granules?
Basophils (dark purple granules), Eosinophils (reddish/pink granules), and Neutrophils (appear colorless but may be light pink/purple).
What is the sequence of differentiation for monocytic development?
Monoblast, Promonocyte, and Mature Monocyte.
How do monocytes differ from granulocytes?
Mature monocytes are larger than granulocytes and do not usually have visible granules under light microscopy.
What are the stages of lymphocyte development?
Lymphoblast, Prolymphocyte, and Mature Lymphocyte.
Where do B-lymphocytes and T-lymphocytes mature?
B-lymphocytes mature in bone marrow, while T-lymphocytes migrate to the thymus.
Identify the characteristics of canine neutrophils.
Most common cell, segmented nucleus with condensed chromatin, pale pink cytoplasm, and slight diffuse granulation.
What are the visual characteristics of feline basophils?
Numerous granules in the cytoplasm that are small and lavender in color.
Describe the unique features of bovine neutrophils.
Similar to dog neutrophils but without visible sex chromatin.
What distinguishes equine eosinophils?
Distinctive large eosinophilic granules.
What is the typical appearance of avian heterophils?
Bilobed or multilobed nucleus with colorless cytoplasm and many eosinophilic granules.