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Support
Framework for body and organs.
Protection
Shields vital organs.
Movement
Muscles pull on bones as levers.
Mineral Storage
Calcium and phosphate for electrolyte balance.
Blood Cell Formation
Red marrow produces blood cells.
Fat Storage
Yellow marrow stores triglycerides.
Hyaline Cartilage
Most abundant; smooth, glassy appearance; found in articular surfaces, nose, trachea.
Elastic Cartilage
Flexible; found in ear and epiglottis.
Fibrocartilage
Tough, absorbs shock; found in intervertebral discs, pubic symphysis, menisci.
Long Bone
Example: femur.
Short Bone
Example: carpals.
Flat Bone
Examples: frontal, sternum.
Irregular Bone
Example: vertebra.
Sesamoid Bone
Example: patella.
Diaphysis
Shaft of compact bone with medullary cavity.
Epiphysis
Ends of spongy bone with red marrow.
Periosteum
Outer membrane of bone.
Endosteum
Inner lining of bone.
Articular Cartilage
Hyaline cartilage covering the ends of bones.
Compact Bone
Dense osteons with central canals, resists compression.
Spongy Bone
Trabeculae with marrow spaces, lightweight, resists forces from many directions.
Organic Bone Composition
Collagen and osteoid provide flexibility.
Inorganic Bone Composition
Hydroxyapatite provides hardness.
Osteogenic Cells
Stem cells that develop into bone cells.
Osteoblasts
Cells that build bone.
Osteocytes
Cells that maintain bone.
Osteoclasts
Cells that break down bone.
Intramembranous Ossification
Develops from mesenchyme; flat bones of skull, clavicle.
Endochondral Ossification
Develops from hyaline cartilage; long bones.
Fontanels
Soft membranous spaces between fetal skull bones that allow brain growth and skull compression during birth.
Longitudinal Growth
Occurs at epiphyseal plate; zones of cartilage proliferate, hypertrophy, calcify, and ossify.
Appositional Growth
Bone added under periosteum, increases width.
Bone Remodeling
Osteoblasts deposit bone, osteoclasts resorb bone.
PTH
Raises blood calcium by stimulating osteoclasts and kidney reabsorption.
Calcitonin
Lowers calcium by inhibiting osteoclasts and increasing excretion.
Growth Hormone
increases chondrocyte activity.
Thyroxine
supports metabolism.
Sex Hormones
stimulate growth, close plates.
Vitamin D
increases calcium absorption.
Fracture Repair Steps
1. Hematoma forms. 2. Soft (fibrocartilaginous) callus forms with hyaline cartilage. 3. Hard (bony) callus replaces cartilage. 4. Remodeling restores original bone shape.
Reduction
realignment of broken bone ends (closed or surgical).
Osteoporosis
low bone density.
Rickets/Osteomalacia
vitamin D deficiency.
Gigantism
GH excess before puberty.
Acromegaly
GH excess after puberty.
Dwarfism
low GH or achondroplasia.
Marfan's
connective tissue defect (long limbs).
Axial Skeleton
skull, vertebrae, ribs, sternum.
Appendicular Skeleton
limbs, pectoral and pelvic girdles.
Male Pelvic Girdle
narrower, heart-shaped inlet, pubic arch < 90°.
Female Pelvic Girdle
wider, shallower, larger inlet, pubic arch > 100° for childbirth.
Bone Markings
• Projections (tuberosity, spine, process) - for muscle attachment. • Depressions (fossa, groove) - for vessels or nerves. • Openings (foramen, canal) - passageways.
Intervertebral Discs
Fibrocartilage pads between vertebrae: outer annulus fibrosus, inner nucleus pulposus.
Herniated Disc
nucleus pulposus protrudes, compressing spinal nerves.
Foot Arches
Arches (medial, lateral, transverse) distribute weight and absorb shock.
Fallen Arches
occur when ligaments/tendons stretch, flattening the arch.
Deviated Septum
vomer & ethmoid.
Cleft Palate
maxilla & palatine.
Scoliosis
lateral curve.
Kyphosis
thoracic hump.
Lordosis
lumbar curve.
Carpal Tunnel
inflammation compresses median nerve.
Joint Classification
Structural: Fibrous (sutures), Cartilaginous (symphysis), Synovial (freely movable). Functional: Synarthrosis - immovable, Amphiarthrosis - slightly movable, Diarthrosis - freely movable.
Synovial Joint Structure
Includes articular cartilage (hyaline), synovial cavity, capsule, ligaments, tendons, bursae, and synovial fluid.
Specific Joints
• Shoulder & Hip - ball-and-socket, multiaxial. • Elbow - hinge, flexion/extension. • Knee - modified hinge, flexion/extension. • Atlas/Axis - pivot, rotation.
Joint Disorders & Injuries
Osteoarthritis - wear & tear. Rheumatoid Arthritis - autoimmune inflammation. Gout - uric acid buildup. Bursitis/Tendonitis - inflamed bursae/tendons. Sprain - stretched ligament. Dislocation - bones forced out of alignment. Separated Shoulder - clavicle/scapula disarticulation.