Excitation-Contraction Coupling in a Skeletal Muscle Cell

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7 Terms

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Acetylcholine is released by the axonal ending, diffuses to the muscle cell, & attaches to ACh receptors on the sarcolemma.

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AChE breaks down ACh, which separates from its receptors.

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Depolarization occurs, & the action potential is generated along the sarcolemma.

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The action potential, carried deep into the cell via the T tubules, causes the SR to release calcium ions.

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The calcium ion concentration at the myofilaments increases; the myofilaments slide past one another, & the cell shortens.

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Within 30 ms after the action potential ends, CA^2+ concentration at the myofilaments decreases.

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The muscle cell relaxes & lengthens.