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sex chromosomes
X and Y chromosomes
associated w/ individual’s sex
autosomes
any chromosome other than sex chromosomes
homologous chromosomes / homologs
chromosomes that are the same size & shape
same genes, diff alleles
homologous pair
pair of homologous chromosomes
gene
segment of DNA, found at specific place on chromosome, that influences trait
allele
particular version of gene
karyotype
The distinctive appearance of all the metaphase or prometaphase chromosomes in an individual, including the number of chromosomes, their length, and their banding patterns.
diploid
organisms that have two versions (homologs) of ea. type of chromosome
2n
haploid
organism containing just one type of chromosome
haploid number
n
number of distinct types of chromosomes in a given cell
maternal chromosome
chromosome from mother
paternal chromosome
chromosome from father
ploidy
number of haploid chromosome sets in cell
polyploid
3+ of ea. type of chromosome in ea. cell
3n, 4n, 5n…
unreplicated chromosome
chromosome consisting of 1 double helix molecule of DNA wrapped around a histone
replicated chromosome
chromosome after DNA replication
consists of 2 identical sister chromatids, ea. containing 1 double helix DNA molecule wrapped around a histone
sister chromatids
two identical chromatids in replicated chromosome
non-sister chromatids
chromatids on diff members of a homologous chromosome pair
not identical
meiosis I
The first cell division of meiosis, in which synapsis, crossing over, and independent assortment occur. It separates homologous chromosomes from each other, producing daughter cells with half as many chromosomes as the parent cell.
meiosis II
The second cell division of meiosis, in which sister chromatids are separated from each other. Meiosis II does not reduce chromosome number and is similar to mitosis.
spindle apparatus
The array of microtubules responsible for moving chromosomes
kinetochores
protein complex that forms on a chromosome during M phase.
Forms at the centromere and serves as a site for microtubule attachment.
Contains motor proteins and microtubule-binding proteins that are involved in chromosome segregation
centromere
region of a replicated chromosome where the two sister chromatids are joined
gametogenesis
The production of gametes (eggs or sperm).
zygote
The cell formed by the union/fertilization of two gametes.
bivalent
4 chromatids from 2 homologous chromosomes
paired, replicated
prophase I, metaphase I
synapsis
pairing of homologous chromosomes
chiasmata
crossing over point
cohesins
proteins that hold sister chromatids together along full length
synaptonemal complex
homologs are held together by a network of proteins
crossing over
chromosome exchange in late prophase I
new combination of alleles
independent alignment/assortment
the alignment of bivalent is independent from others in Metaphase I
new combinations of chromosomes
asexual reproduction
any mechanism of producing offspring that does not involve the production and fusion of gametes
basis of mitosis in eukaryotes
clone
offspring with exact genetic copy
sexual reproduction
any mechanism of producing offspring that does not involve the production and fusion of gametes
variation in offspring
genetic recombination
creation of new combinations of alleles
random fertilization
sperm and egg from different individuals come together without regard for any particular alleles they carry
down syndrome
A human developmental disorder caused by trisomy (3 copies) of chromosome 21.
trisomy
3 copies of a chromosome
2n+1
nondisjunction
homologs or sister chromatids fail to separate during meiosis
monosomy
2n-1
only 1 copy of one of the chromosomes
aneuploid
too many/few of chromosomes of particular type
oogenesis
human egg development
primary oocytes
diploid precursors to eggs