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Vocabulary-style flashcards covering the key terms and concepts from the lecture notes on cells, organelles, transport, cell cycle, tissues, and basic physiology.
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Cell
The basic unit of life; carries out all chemical activities needed to sustain life and is the building block of all living things.
Tissue
Group of cells similar in structure and function.
Nucleus
Control center of the cell; contains genetic material (DNA).
Nuclear membrane
Barrier around the nucleus; double phospholipid membrane with nuclear pores for exchange.
Nucleolus
Sites of ribosome production; ribosomes migrate to the cytoplasm through nuclear pores.
Chromatin
DNA-protein material in the nucleus; condenses to form chromosomes during cell division.
Plasma membrane
Barrier for cell contents; composed of a double phospholipid layer with hydrophilic heads and hydrophobic tails; contains proteins, cholesterol, and glycoproteins.
Cytoplasm
Material outside the nucleus and inside the plasma membrane; includes cytosol, organelles, and inclusions.
Cytosol
Fluid that suspends organelles and elements within the cytoplasm.
Ribosome
Sites of protein synthesis; made of protein and RNA; free or attached to rough ER.
Rough endoplasmic reticulum (RER)
Ribosome-studded ER; site where membrane and secretory proteins are synthesized.
Smooth endoplasmic reticulum (SER)
ER lacking ribosomes; functions in lipid/cholesterol synthesis, fat metabolism, and detoxification.
Golgi apparatus
Modifies and packages proteins; produces secretory vesicles and membrane components.
Lysosome
Contain enzymes that digest nonusable materials within the cell.
Peroxisome
Membranous sacs with oxidase enzymes; detoxify harmful substances and break down free radicals.
Mitochondrion
The cell’s powerhouses; produce ATP through cellular respiration.
Cytoskeleton
Internal framework of the cell made of microfilaments, intermediate filaments, and microtubules.
Microfilaments
Smallest cytoskeletal elements involved in cell movement and shape.
Intermediate filaments
Cytoskeletal components providing mechanical support.
Microtubules
Hollow tubes that determine cell shape and enable organelle movement.
Centrioles
Rod-shaped microtubule structures that direct mitotic spindle formation during cell division.
Cilia
Hair-like projections that move substances across the cell surface.
Flagellum
Long projection that propels the cell.
Microvilli
Finger-like extensions that increase surface area for absorption.
Tight junctions
Junctions that prevent leakage between adjacent cells.
Desmosomes
Strong junctions that anchor cells together to resist tearing.
Gap junctions
Communicating junctions that allow ions and small molecules to pass between cells.
Extracellular fluid
The watery environment outside the cell.
Interstitial fluid
Fluid that surrounds cells in tissues (outside the bloodstream).
Intracellular fluid
Fluid located inside cells; includes nucleoplasm and cytosol.
Diffusion
Movement of solutes from high to low concentration (down a concentration gradient).
Simple diffusion
Unassisted diffusion of lipid-soluble or very small particles through the membrane.
Osmosis
Diffusion of water across a selectively permeable membrane.
Facilitated diffusion
Diffusion that requires a carrier protein to move substances down their concentration gradient.
Filtration
Movement of water and solutes through a membrane due to a hydrostatic pressure gradient.
Active transport
Movement of substances against a concentration gradient; requires energy (ATP).
Solute pumping
Active transport using protein carriers energized by ATP (e.g., Na+/K+ pump).
Bulk transport
Exocytosis and endocytosis; movement of large particles or volumes across the membrane in vesicles.
Exocytosis
Vesicles fuse with the plasma membrane to secrete contents outside the cell.
Endocytosis
Extracellular substances are engulfed by the plasma membrane forming vesicles.
Phagocytosis
Cell eating; ingestion of large particles.
Pinocytosis
Cell drinking; ingestion of fluids and dissolved solutes.
Interphase
The cell’s metabolic period of growth and replication before division.
DNA replication
Duplication of genetic material in preparation for cell division.
Mitosis
Nuclear division producing two identical daughter nuclei.
Prophase
First stage of mitosis; chromosomes condense and centromeres move to poles.
Metaphase
Chromosomes align along the cell’s equator; spindle fibers attach to centromeres.
Anaphase
Sister chromatids separate and move toward opposite poles; cell elongates.
Telophase
Daughter nuclei form; chromatin lengthens; the cell prepares for cytokinesis.
Cytokinesis
Division of the cytoplasm resulting in two separate daughter cells.
DNA
Deoxyribonucleic acid; genetic material that stores the instructions for building proteins.
RNA
Ribonucleic acid; essential for protein synthesis; various forms include mRNA, tRNA, and rRNA.
Transcription
Process of copying a DNA base sequence into a complementary mRNA sequence.
Translation
Process by which the base sequence of mRNA is read to build a polypeptide (protein).
mRNA
Messenger RNA; carries genetic instructions from DNA to the ribosome.
tRNA
Transfer RNA; delivers appropriate amino acids to the ribosome; has an anticodon.
rRNA
Ribosomal RNA; forms the core of ribosome structures and catalyzes protein synthesis.
Codon
Three-nucleotide sequence on mRNA that specifies a particular amino acid.
Anticodon
Three-nucleotide sequence on tRNA complementary to a codon.
Amino acids
Building blocks of proteins; joined by peptide bonds.
Protein synthesis
Process of building proteins from amino acids via transcription and translation.
Gene
DNA segment that provides the blueprint for building a protein.
Protein
A molecule with many functions; acts as enzymes, structural components, and more.
Epithelial tissue
Tissue that covers body surfaces, lines body cavities, and forms glands; functions include protection, absorption, filtration, and secretion.
Epithelium characteristics
Cells fit closely; one free surface; basement membrane; avascular; regenerates easily with nourishment.
Simple epithelium
One cell layer thick; includes squamous, cuboidal, and columnar types.
Stratified epithelium
Two or more cell layers; includes squamous, cuboidal, columnar, and transitional types.
Simple squamous
Single layer of flat cells; lines membranes, lungs, and capillaries.
Simple cuboidal
Single layer of cube-like cells; lines kidney tubules and glands.
Simple columnar
Single layer of tall cells; often with goblet cells; lines digestive tract.
Pseudostratified epithelium
Single layer that looks stratified; often ciliated; lines respiratory tract.
Stratified squamous
Many layers; cells at the free edge are flattened; protective covering in skin, mouth, esophagus.
Stratified cuboidal
Two layers of cuboidal cells; rare; found in ducts of large glands.
Stratified columnar
Surface cells are columnar; rare; found in ducts of large glands.
Transitional epithelium
Shape changes with stretching; lines urinary system organs.
Glandular epithelium
Glandular tissue formed by secreting cells; endocrine (ductless) and exocrine (ducts).
Endocrine gland
Ductless gland; secretes hormones into the blood.
Exocrine gland
Gland that secretes to the epithelial surface via ducts (e.g., sweat, oil glands).
Connective tissue
Found throughout the body; binds, supports, protects; most abundant and distributed tissue.
Extracellular matrix
Non-living material surrounding living cells; composed of ground substance and fibers.
Ground substance
Water-rich medium with adhesion proteins and polysaccharides.
Collagen fibers
Fibers providing tensile strength in connective tissue.
Elastic fibers
Fibers that provide elasticity to tissues.
Reticular fibers
Fine network fibers that support organs.
Bone tissue (osseous tissue)
Bone cells in lacunae; hard matrix of calcium salts; collagen fibers; protects and supports.
Hyaline cartilage
Most common cartilage; rubbery matrix with collagen; fetal skeleton is hyaline.
Elastic cartilage
Cartilage that provides elasticity (e.g., external ear).
Fibrocartilage
Highly compressible cartilage; cushions between vertebrae.
Dense connective tissue
Matrix rich in collagen fibers; fibroblasts; includes tendons and ligaments.
Areolar connective tissue
Widely distributed; soft, pliable tissue; contains all fiber types; soaks up fluid.
Adipose tissue
Fat tissue; adipocytes store lipid; insulates, protects organs, and stores fuel.
Reticular connective tissue
Delicate network of reticular fibers; forms supporting stroma in lymphoid organs.
Blood
Blood cells in a fluid matrix; fibers visible during clotting; transport vehicle for materials.
Muscle tissue
Tissue that produces movement; three types: skeletal, cardiac, smooth.
Skeletal muscle
Voluntary, attached to bones, striated, multiple nuclei per cell.
Cardiac muscle
Heart muscle; pumps blood; involuntary; striated; intercalated disks.
Smooth muscle
Involuntary muscle; surrounds hollow organs; no visible striations; single nucleus.
Nervous tissue
Neurons and supporting cells; conducts impulses; irritability and conductivity.
Tissue repair: Regeneration
Replacement of damaged tissue by the same kind of cells.
Fibrosis
Repair by dense fibrous connective tissue (scar tissue).