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One-Dimensional
looking for a single cause
Multidimensional
looking for a systemic cause
Genes
long molecules of DNA at various locations on chromosomes, within cell nucleus
Chromosomes
the chain-like structures within a cell nucleus that contain the genes
Genes
carries of the information we inherit from our parents
How many chromosomes are there?
46 Chromosomes,
How many pairs of chromosomes are there?
23 Pairs
How many pairs of autosomes are there?
22 Pairs of Autosomes,
How many sex chromosomes are there?
1 pair Sex Chromosomes
XX Chromosomes
female
XY Chromosomes
male
Phenotypes
observable characteristics
Genotypes
unique genetic makeup
Polymorphisms
naturally occurring variations of genes
Polygenic
influenced by multiple genes or by multiple polymorphisms of genes with any one gene having only very small effects
Endophenotypes
genetic mechanisms that ultimately contribute to the underlying problems causing the symptoms and difficulties experienced by people with psychological disorders
Basic Genetic Epidemiology
statistical analysis of family, twin, and adoption studies; if the disorder can be inherited and how much is attributable to genetics
Advanced Genetic Epidemiology
studies the factors that influence the disorder
Gene Finding
what gene influences the behavior
Molecular Genetics
biological analysis of individual DNA samples; biological processes genes affect to produce symptoms of the disorder
Family Studies
examine behavioral pattern or emotional trait in the context of the family
Proband
Family member with the trait singled out for study
The first person in the family to be identified as possibly having genetic disorder and who may receive genetic counseling or testing
Adoption Studies
identify adoptees who have a particular behavioral pattern or psychological disorder and attempt to locate first-degree relatives who were raised in different family settings
Twin Studies
usually conducted to identical twins because they share genetic makeup
Epigenetics
factors other than inherited DNA sequence, such as new learning or stress, that alter the phenotypic expression of genes
Neuroscience
study of the nervous system, especially the brain to understand behavior, emotions, and cognitive processes
Dopamine
pleasure, reward, motivation system
Acetylcholine
Memory and muscle
Norepinephrine
Concentration
GABA (Gamma-Aminobutyric Acid)
Inhibitory/brake, calming
Serotonin (5-HT)
mood
Epinephrine
fight or flight
Glutamate
excitatory, learning, and memory
Endorphin
natural pain killers
high vs low dopamine
Schizophrenia — Parkinson’s
low acetylcholine
Alzheimer’s (Dementia)
high vs low norepinephrine
Mania — Depression
high vs low GABA
Relaxation — Anxiety/OCD