Pharmacology - Antihistamines/Anticholinergics: Dimenhydrinate

Flashcards covering key concepts and information related to Dimenhydrinate, an antihistamine/anticholinergic medication.

Therapeutic Use of Dimenhydrinate

Antiemesis, vertigo, motion sickness.

Adverse Drug Reactions of Dimenhydrinate

Sedation, anticholinergic effects (dry mouth, urinary retention, constipation).

Interventions when administering Dimenhydrinate

Monitor clients when ambulating, for anticholinergic effects, bowel elimination patterns, and vital signs

Client Instructions for Dimenhydrinate

Do not take prior to driving, sit or lie down if feeling drowsy, change positions gradually, suck on hard candy or chew gum, sip water, increase fluid and fiber intake, increase activity levels

Contraindications for Dimenhydrinate

Known hypersensitivity, newborn infants, glaucoma, and preterm

Method of action for Dimenhydrinate

Blocks the release of histamine at H1 receptors in the inner ear connected to the CTZ

Drug class for Dimenhydrinate

Antihistamine

Drug class for Aprepitant

NK1 Antagonists

Method of action for Aprepitant

Blocks NK1 receptors that transmit signals that cause nausea and vomiting

Side effects for Aprepitant

Bradycardia, deep vein thrombosis, and renal insufficiency

Contraindications for Aprepitant

Use of primozide, hypersensitivity, and pregnancy