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What is an advantage of using amoxicillin over penicillin V?
Slightly broader spectrum
Which antifungal agent for oral candidiasis is available as an aqueous solution?
Nystatin
Contraindicated in a pregnant patient, has reduced effectiveness if taken with dairy products, antacids, or calcium supplements, and concentrates in GFC
Tetracycline
most likely to produce an allergic reaction
Penicillin
has the highest incidence of GI complaints of any of the antibiotics
Erythromycin
can cause black pigmentation of mandibular and maxillary alveolar bone and the hard palate.
Minocycline
Associated with a severe drug interaction with alcohol
Metronidazole
Which 2 local anesthetic agents have the potential to cause methemoglobinemia as an adverse effect?
Prilocaine and Articaine
Nitrous oxide, as used in the dental office, maintains the patient in stage _____ of Guedel's system of stages and planes
I
The loss of respiratory control (i.e., diminished carbon dioxide response, paralysis of intercostal muscles) first occurs during which of Guedel's stages of anesthesia?
II
Dental pain following a simple tooth extraction is best managed with which of the following choices?
Ibuprofen
The following are conditions for which opioid analgesics should be used with extreme caution or not at all except which one?
Hypertension
Which is an advantage of the NSAIDs over the opioids for the management dental pain in an opioid addict?
They are not addictive
destroys or inhibits the growth of microorganisms such as bacteria
antibacterial
the disease-producing power of the microorganism
virulence
inhibits or kills organisms that can produce infection
antiinfective
inhibits or retards the multiplication or growth of bacteria
bacteriostatic
high risk for addiction or abuse
Schedule II
available over the counter
Schedule V
cannot be refilled more than 5 times within 6 months
Schedule III
Cannot be telephoned into pharmacy
Schedule II
regulates manufacture and distribution of substances (with abuse potential) and ultimately determines whether a drug is considered a controlled substance and its schedule
DEA
responsible for creating pregnancy drug subsections and lactation subsections
FDA
Regulates the labeling and advertising of prescription drugs
FDA
Prohibits the false advertising of foods, nonprescription (OTC) drugs, and cosmetics
FTC
-Regulates the trade practices of drug companies
FTC
a
before
ac
before meals
bid
twice a day
c
with
cap
capsule
d
day
disp
dispense
gm
gram
gr
grain
gtt
drop
h
hour
hs
at bedtime
p
after
pc
after meals
PO
by mouth
prn
as needed
q
every
qid
4 times a day
s
without
sig
write(label)
ss
one half
T/F:
When a drug has affinity for a receptor and produces no effect, it is called an agonist
fasle
Most drugs are excreted through what mechanism?
glomerular filtration
The route of administration of a drug affects the
both the onset and duration of response
The following choices refer to adverse reactions involving exaggerated effects on target tissues EXCEPT
caused by a nontherapeutic action of a drug
Which herbal supplement products have been proven effective in protecting against plaque and gingivitis?
Triclosan and Xylitol
Physical dependence
is established by withdrawal syndrome and refers to the altered physiologic state that results from constantly increasing drug concentrations
Which of the following choices is NOT a symptom of ethyl alcohol intoxication?
constricted pupils
Which substance is associated with a deficiency of coagulation factors after chronic abuse?
Ethyl alcohol
What should the dental hygienist do first if a patient reports a suspected adverse drug effect?
Determine what drugs the patient is taking
Which dental anesthetic is contra-indicated for a pregnant woman?
Bupivicaine
What would be the best choice for dental anesthesia in a pregnant patient?
Lidocaine
The greatest risk to the fetus from exposure to drugs occurs
during the first trimester
Which of the following choices would occur during a generalized discharge of the sympathetic nervous system?
Gylcogen breakdown
The neurotransmitter released from a preganglionic neuron in the sympathetic division of the autonomic nervous system is
acetylcholine
The acronym SLUD denotes adverse reactions associated with administration of _____ agents.
cholinergic
Anticholinergics
Decrease esophageal and gastric motility
A drug with anticholinergic side effects might exhibit all of the following except:
increased salivation
Which of the following categories of autonomic nervous system (ANS) agents can cause an acute rise in intraocular blood pressure in patients with glaucoma?
Anticholinergic
Adrenergic agents should be used with caution in patients with (1) angina, (2) hypertension, (3) hypothyroidism
1 & 2
Norepinephrine is the neurotransmitter of the
post-ganglionic nerve of the sympathetic division of the autonomic nervous system.
Which type of agent such as donepezil (Aricept) has been FDA approved for the treatment of dementia?
Cholinergic agents
Which type of autonomic drugs are first-line therapy for overactive bladder (OAB)?
Anticholinergic agents
Indications for parasympathetic autonomic nervous system (PANS) drugs include all except:
treatment of bronchial asthma
Which is a major disadvantage of parenteral diazepam?
thrombophlebitis
All are factors that contribute to the effectiveness of benzodiazepine EXCEPT
Highly ionized form?
The SSRIs are first-line treatment for
major depressive disorder
All are adverse reactions to first-generation antipsychotic medications EXCEPT
excessive salivation
What antiseizure medication is most likely to cause gingival overgrowth?
Phenytoin (Dilantin)
The drug group of choice for status epilepticus seizures is parenteral
diazepam (Valium)
Each of the following effects is a characteristic of channel-blocking agents EXCEPT
orthostatic hypotension
-artan
Angiotensin Receptor Blocker (ARB)
-Pril
ACE inhibitor
-olol
β-blocker
-dipine
calcium channel blocker
gingival enlargement is an adverse drug reaction
calcium channel blockers
may cause chronic unproductive cough
ACE Inhibitors
What antilipemic agent is commonly prescribed for trigeminal neuralgia?
Carbamazepine
What antilipemic medication has been known to produce osteomalacia?
Phenytoin
Gingival enlargement as a consequence of phenytoin therapy most commonly affects the __________ facial gingiva.
maxillary anterior
most common formulation of local anesthesia used in dentistry today
Lidocaine 2% 1:100,000 epi
indicated for a lengthy dental procedure based on duration of action
Bupivacaine (Marcaine) 0.5% w/ 1:200,000 epi
Pregnant patient in 2nd trimester
Lidocaine 2% w/ 1:100,000 epi
use should be avoided in minors
Prilocaine 4% w/ 1:200,000 epi