immuno in quiz 7.3-7.4 8.1-8.2

Which of the following pairs of molecules are NOT involved in the induction of apoptosis by cytotoxic T cells?

A. Perforin and granzyme

B. Caspase 3 and 7

C IL-10 and TGFB 

D. Fas and FasL

C IL-10 and TGFB 

2. Antimicrobial peptide production, neutrophil recruitment, and IL-17 release are all mediated by ___ in response to ___

A. ILC1: extracellular pathogens

B. ILC1: bacterial infection

C. ILC3: intracellular pathogens

D. ILC3: fungal infection

D. ILC3: fungal infection

3. Single positive thymocytes upregulate S1 PR1 in order to follow the concentration gradient of S1 P. The role of S1P in this process is most analogous to which of the following classes of cytokines?

A. Interleukins

B. Interferons

C. Chemokines

D. Hematopoietins

C. Chemokines

4. Which of the following is an accurate statement pertaining to the functional relationship between MHC and natural killer (NK) cells?

A. MHC-I binds to activating NK receptors

B. MHC-II binds to activating NK receptors

C. MHC-I binds to inhibitory NK receptors

D. MHC-II binds to inhibitory NK receptors

C. MHC-I binds to inhibitory NK receptors

5. Which of the following antigen presenting cells is essential for activating naïve T cells in secondary lymphoid organs?

A. Dendritic cells

B. Macrophages

C. Monocytes

D. B cells

A. Dendritic cells

6. ILCs are most analogous to ___ because their effector functions primarily involve

Á. CD4 T cells: direct cytotoxicity

B CD4 T cells: cytokine secretion

C. CD8 T cells: direct cytotoxicity

D. CD 8 T cells: cytokine secretion

B CD4 T cells: cytokine secretion

7. Which of the following is a transcription factor that promotes Type 1 immune response to intracellular infection?

A.T-bet

B. Bcl6

C. Foxp3

D. IFNY

A.T-bet

8. NK cells are most important for controlling which of the following types of infections?

A. Extracellular bacteria

B. Fungi

C. Viruses

D. Parasites

C. Viruses

9. Which of the following occurs in naïve T cells following TCR activation without costimulation?

A. Proliferation

B. Somatic recombination

C. Apoptosis

D Anergy

D Anergy

10. Which of the following is an accurate statement pertaining to ILCs?

ILCs are derived from the myeloid cell lineage

ILCs are activated in an antigen-independent manner

C. ILCs phagocytose pathogens and function as APCs

D. ILCs require successful VDJ recombination during their development

ILCs are activated in an antigen-independent manner