#10.7 Brain Mechanism of Hunger

Arcuate Nucleus (ARC)

Located in the hypothalamus

hunger- & satiety-sensitive neurons

Arcuate Nucleus (ARC) <

sets of neurons (2&)

hunger-sensitive neurons

Arcuate Nucleus (ARC) <

activated by ghrelin, low glucose, and low leptin

hunger-sensitive neurons

Arcuate Nucleus (ARC) <

increases eating and inhibits satiety neuonrs

satiety-sensitive neurons

Arcuate Nucleus (ARC) <

activated by CCK, insulin, high leptin, and high glucose

satiety-sensitive neurons

Arcuate Nucleus (ARC) <

increases satiety signals and inhibits hunger neurons

Paraventricular Nucleus (PVN)

HYPOTHALAMUS <

regulates satiety, meal size, autonomic nervous system, and metabolism

Paraventricular Nucleus (PVN)

HYPOTHALAMUS <

regulates satiety by activating CCK and sending signals to stop eating

Paraventricular Nucleus (PVN)

HYPOTHALAMUS <

its inhibition results to eating huge meals

Lateral Hypothalamus (LH)

HYPOTHALAMUS <

feeding center

Lateral Hypothalamus (LH)

HYPOTHALAMUS <

increases hunger & insulin secretion, makes food taste better (DOPAMINE), and controls stomach secretions

Lateral Hypothalamus (LH)

HYPOTHALAMUS <

damage results to refusal to eat

Ventromedial Hypothalamus (VMH)

HYPOTHALAMUS <

satiety center

Ventromedial Hypothalamus (VMH)

HYPOTHALAMUS <

damage results to overeating, weight gain, increased insulin, and increased fat storage