Chapter 50 H2 antagonists exam 4

0.0(0)
studied byStudied by 0 people
GameKnowt Play
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/6

encourage image

There's no tags or description

Looks like no tags are added yet.

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

7 Terms

1
New cards

What are H2 receptor antagonists?

–Reduce acid secretion

–All available OTC in lower dosage forms

–Most popular drugs for treatment of acid-related disorders

Famotidine (Pepcid)

2
New cards

H2 antagonists mechanism of action:

–Competitively block the H2 receptor of acid-producing parietal cells

–Reduced hydrogen ion secretion from the parietal cells

–Increase in the pH of the stomach 

3
New cards

Drug effect of H2 antagonists:

Suppress acid secretion in the stomach

4
New cards

Indications for H2 antagonists

Gastroesophageal reflux disease (GERD)

PUD

Erosive esophagitis

Adjunct therapy to control upper GI bleeding

Zollinger-Ellison syndrome (tumors)

5
New cards

Adverse effects of H2 antagonists:

–Overall, very few adverse effects. Remarkably low incidence of adverse effects, less than 3% of cases

–CNS adverse effects, including confusion occurs in < 1% but sometimes seen in older adults

6
New cards

H2 antagonist drug interactions:

Smoking has been shown to decrease the effectiveness of H2 blockers.

7
New cards

For best results the H2 blocker should be taken how long before antacids?

1 to 2 hours