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Longitudinal growth
growth in length of long bones
Stage 1 Longitudinal growth
New cartillage forms while chondroblasts divide to create cartilage matrix
Stage 2 Longitudinal growth
Cartilage is replaced with bone and everything else invades the area
Appositional growth
Process that enlarges the thickness and diameter of bone
Stage 1 of appositional growth
Osteoblasts within periosteum secretes new bone matrix on external bone surface
What do the osteoblasts in Stage 1 of appositional growth form
Circumferential lamellae
Stage 2 of appositional growth
Osteoclasts remove old bone from endosteal surface and enlarge the marrow cavity
What secretes the growth hormone?
The pituitary gland
What does the growth hormone do?
stimulates division of chondroblasts in epiphyseal plate
stimulates division and activity of osteoblasts
Increases calcium retention
Increases bone mineralization
Childhood hyposecretion
Dwarfism
Childhood hyper secretion
gigantism
Adult hypersecretion or GH abuse
Acromegaly
What glands secrete the parathyriod hormone
parathyriod hormones
Parathyriod hormone function:
Increases blood calcium levels and is the receptor when low blood calcium
Why is vitamin D important
It increases calcuim absorbtion
What is calcitonin secreted by
Thyriod gland
Purpose of calcitonin
Reduced blood calcium
Sex hormones that promote bone density
Estrogen, testosterone, and adrenal cortex
Sex hormone that promote bone mass
Testosterone and adrenal cortex
Sex hormones that inhibit osteoclasts and stimulates osteoblast activity
Estrogen and adrenal cortex