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Vocabulary flashcards for key concepts in biochemistry, cells, energy, molecular genetics, regulation, evolution, and ecology.
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Ionic Bond
Bond where electrons are transferred.
Covalent Bond
Bond where electrons are shared. Can be polar (unequal sharing) or non-polar (equal sharing).
Hydrogen Bond
Weak bond between hydrogen and negatively charged items.
Hydrophobic Interactions
How non-polar compounds congregate together, characteristic of lipids.
Acid
A substance with a pH less than 7, indicating a higher concentration of H+ ions.
Base
A substance with a pH greater than 7, indicating a lower concentration of H+ ions.
Cohesion
Attraction between water molecules.
Adhesion
Attraction of water molecules to other charged compounds.
Dehydration Synthesis
Process by which monomers join together to form polymers with the loss of water.
Hydrolysis
Process by which polymers are broken down into monomers with the input of water.
Monosaccharide
Monomer of carbohydrates, such as glucose.
Disaccharide
Two monosaccharides joined together.
Polysaccharide
Three or more monosaccharides joined together, such as starch, glycogen, or cellulose.
Saturated Fat
Lipid with single bonds between carbons.
Unsaturated Fat
Lipid with at least one double bond between carbons.
Phospholipid
Lipid that makes up cell membranes and is amphipathic (hydrophilic and hydrophobic).
Amino Acid
Monomer of proteins, containing a carboxyl group, amino group, central carbon, and variable R group.
Primary Structure
The sequence of amino acids in a protein.
Secondary Structure
The structure where hydrogen bonds form beta pleated sheets or alpha helices in a protein.
Tertiary Structure
The globular structure of a protein formed from disulfide bridges, hydrogen bonds, hydrophobic interactions and ionic bonding.
Quaternary Structure
The structure of a protein with more than one polypeptide chain.
Nucleotide
Monomer of nucleic acids, made up of a sugar, phosphate, and base.
DNA
Double stranded nucleic acid that stores genetic information, contains deoxyribose, and uses the bases A, G, C, and T.
RNA
Single stranded nucleic acid that plays a role in protein synthesis, contains ribose, and uses the bases A, G, C, and U.
Enzyme
Biological catalyst (made of protein) that speeds up rate of chemical reactions by lowering activation energy.
Active Site
The location on an enzyme where the substrate binds and the reaction occurs (exposed R groups).
Catabolic Reaction
Reaction in which enzymes break down a substance.
Anabolic Reaction
Reaction in which enzymes build up substances.
Substrate
The substance on which an enzyme acts.
Competitive Inhibition
Inhibition where something competes for the active site, can be overcome with more substrate.
Non-Competitive Inhibition
Inhibition where something attaches at the allosteric site and changes the shape of enzyme so it is not functional, can not be overcome with more substrate.
Coenzyme
Organic molecule that interacts with enzymes to put them into the right structure to do work (NAD and Vitamin B).
Cofactor
Inorganic molecule that interacts with enzymes to put them into the right structure to do work (Zinc, Magnesium).
Prokaryotic Cell
Cell lacking membrane-bound organelles and a nucleus.
Eukaryotic Cell
Cell containing membrane-bound organelles and a nucleus.
Nucleus
Organelle that holds DNA and the nucleolus where ribosomal subunits are made.
Mitochondria
Organelle with a double membrane where ATP is made during cellular respiration.
Ribosome
Organelle that translates RNA into protein.
Endoplasmic Reticulum
Membranous organelle connected to the nucleus, smooth synthesizes lipids, rough synthesizes proteins.
Golgi Complex
Organelle that packages molecules in membranes and signals for export.
Lysosome
Animal cell organelle that contains enzymes used for intracellular digestion and apoptosis.
Chloroplast
Plant cell organelle with a double membrane where photosynthesis (glucose synthesis) occurs.
Cell Wall
Plant cell organelle composed of a middle lamella, primary cell wall, and secondary cell wall.
Endosymbiont Theory
Theory that all eukaryotic cells came from bacterial cells that lived together.
Cell Membrane
Separates the internal environment of the cell from the external environment. Composed of a phospholipid bilayer (selectively permeable; amphipathic).
Simple Diffusion
From high to low concentration- small and uncharged move freely through phospholipids (passive transport).
Facilitated Diffusion
Large or charged molecules move from high to low concentration with a protein carrier (passive transport).
Active Transport
Molecules move from low to high concentration, requires ATP, and a protein.
Endocytosis
Phagocytosis (solid) and pinocytosis (liquid) process where the membrane surrounds and forms vesicles.
Exocytosis
Releasing of material using vesicles fusing with membrane.
Osmosis
Diffusion of water using a selectively permeable membrane (passive transport).
Hypertonic
Solution with high solute concentration.
Hypotonic
Solution with low solute concentration.
Isotonic
Solution with equal solute concentration.
Neuron
A nerve cell; the basic building block of the nervous system.
Neurotransmitter
A chemical messenger that carries signals between neurons.
Depolarization
The process during the action potential when sodium is rushing into the cell causing the interior to become more positive.
Repolarization
The process during the action potential when sodium and potassium are exchanged through the sodium-potassium pump.
1st Law of Thermodynamics
Matter and energy are not created but change form.
Cellular Respiration
Process that makes ATP for cell use; uses glucose and oxygen and makes waste products of carbon dioxide and water; occurs in mitochondria; NADH is used as an electron carrier.
Glycolysis
Occurs in cytoplasm; rearranges the bonds in glucose molecules, releasing free energy to form ATP from ADP anaerobic process.
Krebs Cycle
Occurs in mitochondrial matrix; pyruvate is oxidized further and carbon dioxide is released ; ATP is synthesized from ADP and inorganic phosphate via substrate level phosphorylation and electrons are captured by coenzymes (NAD+ and FAD).
Electron Transport Chain
The electron transport chain captures electrons, pumping H+ ions into the inter-membrane space of the mitochondria.
Photosynthesis
Photosynthetic organisms capture free energy present in sunlight and use water and carbon dioxide to make carbon products and free oxygen.
Light-Dependent Reactions
Photosystems I and II (chlorophyll and proteins) are embedded in the internal membranes of chloroplasts. They pass electrons through an electron transport chain (ETC).
Light-Independent Reactions
Carbon fixation occurs (carbons of CO2 used to make sugar); occurs in stroma of chloroplasts; ATP and NADPH generated by light-dependent reactions are used to assemble glucose.
Anaerobic Fermentation
No oxygen; cell only goes through glycolysis followed by fermentation.
Mitosis
Cell division occurring after interphase, resulting two identical cells or clones.
Meiosis
Occurs after interphase, takes diploid cells and reduces the chromosome number to haploid.
Law of Dominance
One allele will be expressed over another.
Law of Segregation
Alleles pairs separate from each other during meiosis.
Law of Independent Assortment
Alleles assort independently during meiosis IF they are on separate chromosomes.
Incomplete Dominance
red X white pink; both protein product are expressed and blended.
Codominance
red x white red and white; both protein products are equally expressed ex.AB blood types.
Epistasis
One gene affects expression of another.
Linked Genes
Genes on same chromosome that are inherited together (can be unlinked by crossing over); recombination frequency calculated by recombinants/total; used for chromosome mapping.
Polygenic
Continuous variation, many genes affect one trait- height, color.
Autosomes
22 pairs of chromosomes in human genome.
Sex Chromosomes
1 pair of chromosomes in human genome.
Nondisjunction
Failure of chromosomes to separate at anaphase of meiosis.
Mutation
Any change of DNA sequence, can be inheritable if it is in egg or sperm.
DNA
Deoxyribose nucleic acid, double helix, antiparallel strands made of nucleotides each with a phosphate + 5C deoxyribose sugar + nitrogen base.
DNA Replication
Process of making exact copies of DNA semi conservatively (original strand is copied).
Transcription
Making mRNA in nucleus, enzyme RNA pol reads the DNA in 3’ to 5’ direction and synthesizes complementary mRNA.
Translation
mRNA code is read and matched with tRNA (brings amino acids) to construct a polypeptide using the ribosome.
Negative Feedback
Mechanisms that maintain dynamic homeostasis for a particular condition (variable) by regulating physiological processes, returning the changing condition back to its target set point.
Positive Feedback
Mechanisms that amplify responses and processes in biological organisms, initiating an additional response that produces system change.
Signal Transduction
The process by which a signal is converted to a cellular response.
Natural Selection
Major mechanism of change over time – Darwin’s theory of evolution.
Adaptation
A genetic variation that is favored by selection and is manifested as a trait that provides an advantage to an organism in a particular environment.
Fitness
The ability to survive and reproduce.
Hardy-Weinberg Equilibrium
A mathematical model used to calculate changes in allele frequency, providing evidence for the occurrence of evolution in a population.
Speciation
An evolutionary process by which 2 or more species arise from 1 species and 2 new species can no longer breed and reproduce successfully.
Habitat
Type of area an organism lives.
Niche
Role of an organism in ecosystem.
Exponential Growth
J-shaped, unlimited growth.
Logistic Growth
S-shaped, limited growth.
Carrying Capacity
Maximum population supported by habitat.
Symbiosis
Species interaction.
Mutualism
+/+ interaction.