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List and describe the five multiple factors of how harmful toxicity is.
Dose: How much was absorbed
Duration: How long was the exposure
Entry: Was it ingested Inhaled Absorbed through skin
Interactions: Taken with other medications Substances
Byproducts(metabolites): What did it break down into
List and describe the 6 methods of collecting physical evidence.
Document, photograph, and collect all substances and what they may have contained
Plants/Wet: Dry and place in paper bag
Syringes/needles: Glass containers labeled 'Biohazard'
Dry: paper bindle & plastic bag
List and describe how physical evidence is tested
Microscope Identification
Microcrystalline Testing: Dry substances into crystal & measure unique light frequency
Gas Chromatography: Determine visual 'fingerprints'
Describe what happened in 1982 in Illinois.
Patients arrived at local hospitals with bizarre symptoms-headaches, dizziness, confusion. They quickly died after arrival from what appears to be lack of oxygen. Tylenol was found to be in the homes of each victim, the bottles revealed potassium cyanide.
What do forensic investigators must be able to determine
What poison was used, Why it was taken, By who
What facts do forensic investigators have to keep in mind
Less than 1% of homicides result from poisoning, accidental overdoses are the most common.
List the 8 methods by which substances can enter the body.
Buccal, Oral, Pulmonary, Transdermal, Ocular, Nasal, Sublingual, Vaginal/Anal
Why is smoking harmful
Smoke is harmful for the lungs
List the 3 ways a person can be exposed to a drug.
Intentional- taken a drug to treat illness or to relieve pain
Accidental- unintentionally taken
Deliberate- suicide
List the 5 types of drugs.
Stimulants, Narcotics, Depressants, Alcohol, Steroids
Name 3 types of alcohol.
Beer, Wine, Liquor
Describe what happens to the body and brain when under the influence of depressants
slows messages between the body and brain signals from the eyes and other senses reach the brain slowly
Describes what happens to the body and brain when under the influence of stimulants.
Creates fake messages in the brain, telling the body that it's under stress
Chemical elements that have the same number of protons, but different numbers of neutrons
Isotopes
The study of the adverse effects of chemicals or physical agents on living organisms
Toxicology
A substance naturally produced by a living thing that can cause illness or death in humans
Toxin
Rapid involuntary jerking of the eyeball
Nystagmus
A natural or manufactured substance that can cause severe illness or death if ingested, inhaled, or absorbed through the skin
Poison
A type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action
Venom
Effects of a toxin occurring almost immediately (hours or days) after an exposure
Acute Toxicity
The combined effect of substances that decreases their individual effects
Antagonism
The combined effect of substances that exceed the sum of their individual effects
Synergism
Lethal dose for 50 percent of a given population
LD50
Continuing exposure to toxins over a long period of time
Chronic Exposure
The degree to which a substance is poisonous or can cause illness
Toxicity
An organic compound that complexes with a metal to form a ring structure
Chelating Agent
The time it takes for half a sample to decay
Half-life
One-millionth of a gram
Microgram
A physical or chemical phenomenon or a process in which atoms, molecules or ions enter some bulk phase-liquid or solid material
Absorption
A substance affecting the nervous system by increasing alertness, attention, and energy, as well as elevating blood pressure, heart rate, and respiration
Stimulan