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Mental health
"the successful adaptation to stressors from the internal or external environment evidenced by thoughts, feelings, and behaviors that are age-appropriate and congruent with local and cultural norms" (Robinson)
Mental illness
"maladaptive responses to stressors… evidenced by thoughts, feelings, and behaviors that are incongruent with local and cultural norms, and interfere with the individual's social, occupational, and/or physical functioning"
DSM-5-TR definition of mental disorder
a syndrome of clinically significant disturbance in cognition, emotional regulation, or behavior reflecting dysfunction in psychological/biological/developmental processes; usually causes significant distress/disability. ⭐ An expected/culturally approved response to a stressor or loss (e.g., grief) is NOT a mental disorder
Anxiety
discomfort/apprehension related to fear of impending danger; source often unknown
Grief
subjective feeling of sorrow/sadness with emotional, physical, social responses to loss
Neurosis (older term, not a current DSM category)
excessive anxiety expressed/altered through defense mechanisms; no loss of reality contact, but functioning impaired
Psychosis
significant thought disturbance, impaired reality testing → delusions, hallucinations, disorganized speech/catatonia
Anosognosia
unawareness of one's own psychological problems/illness (seen in psychosis)
Hippocrates (~400 BCE)
First to view mental illness as physical, not supernatural; theory of 4 humors (4 humors = body fluids) (blood, black bile, yellow bile, phlegm)
Middle Ages (CE 500–1500)
Mental illness → recognized as medical problem; first asylums
Benjamin Rush
"Father of American psychiatry"; humanistic care but still used bloodletting/restraints. (free clinics for the poor)
First U.S. state hospital
Philadelphia, mid-1800s
Dorothea Dix
Lobbied for system of state asylums (1800s); believed mental illness was curable ( & that state hospitals should provide humanistic therapeutic care)
Linda Richards
First American psychiatric nurse (graduated 1873, New England Hospital for Women and Children)
1882
First school of psychiatric nursing — McLean Asylum, Massachusetts
1955
Psychiatric nursing became required curriculum in all undergrad nursing programs
National Mental Health Act of 1946
Funded education of psychiatrists, psychologists, psychiatric nurses; led to graduate-level psych nursing education (around the same time antipsychotic meds helped pts w/ psychosis)
1960s
Community mental health movement began
Maslow's Hierarchy of Needs (bottom → top)
Physiological → Safety/Security → Love/Belonging → Self-Esteem → Self-Actualization
Incomprehensibility
inability to understand the motivation behind behavior
Cultural relativity
"normal" vs "abnormal" depends on the culture's own norms
Alarm reaction
fight-or-flight responses initiated
Stage of resistance
body adapts to stressor; symptoms may disappear if adaptation succeeds
Stage of exhaustion
prolonged stress depletes adaptive energy → diseases of adaptation (headaches, CAD, ulcers, colitis, mental disorders) → can lead to death if unresolved
Mild
Sharpens senses, ↑ motivation/productivity, ↑ perceptual field, optimal learning/functioning; uses simple coping mechanisms (crying, pacing, talking to someone, exercise, drinking, eating, cursing, yawning, laughing etc.)
Moderate
↓ perceptual field, less alert to surroundings, ↓ attention span/concentration, ↑ muscle tension/restlessness; may need help problem-solving; ego defense mechanisms activate
Severe
Perceptual field greatly diminished — focus on one detail or scattered on many; extremely limited attention span; physical sx (headache, palpitations, insomnia) + emotional sx (confusion, dread, horror)
Panic
Unable to focus on anything; misperceptions common; loss of contact with reality possible (hallucinations/delusions); feeling of terror, "going crazy"; can be life-threatening if prolonged
Compensation
Covering up a weakness by emphasizing a more desirable trait
Denial
Refusing to acknowledge a real situation/feelings
Displacement
Transferring feelings from true target to a safer/less threatening one
Identification
Increasing self-worth by adopting traits of an admired person
Intellectualization
Avoiding emotions by focusing on logic/facts
Introjection
Integrating another's beliefs/values into one's own ego
Isolation
Separating a thought/memory from its associated feeling
Projection
Attributing one's own unacceptable feelings to another person
Rationalization
Making excuses/logical-sounding reasons to justify unacceptable behavior
Reaction formation
Expressing the opposite of one's true (unacceptable) feelings
Regression
Retreating to an earlier developmental level under stress
Repression
Involuntary blocking of unpleasant feelings/experiences
Sublimation
Rechanneling unacceptable drives into socially acceptable activities
Suppression
Voluntary blocking of unpleasant feelings ("I'll think about it tomorrow")
Undoing
Symbolically canceling out an intolerable act/thought
Mourning
the grief-related emotions/behaviors process; duration is individual/variable
Prolonged grief disorder
new DSM-5-TR diagnosis (Trauma and Stressor-Related Disorders category); intense distress + impaired functioning enduring beyond 12 months after the loss
Psychobiology
study of biological foundations of cognitive, emotional, behavioral processes
Neuroendocrinology
study of interaction between nervous system & endocrine system, and hormone effects on behavior
Genetics
study of biological transmission of physical/behavioral characteristics parent → offspring
Genotype
total set of genes coded in DNA
Phenotype
physical manifestation of genotype (eye color, height, etc.) — not purely genetic, can be environmentally influenced too
Psychoneuroimmunology (PNI)
study of relationship between immune system, nervous system, and psychological processes (thinking/behavior)
Forebrain
Cerebrum, Diencephalon
Midbrain
Mesencephalon
Hindbrain
Pons, Medulla, Cerebellum
Cerebrum
2 hemispheres joined by corpus callosum (200 million axons); outer layer = cerebral cortex (gray matter = "thinking" structures); left hemisphere = logic/problem-solving; right hemisphere = creative/affect/spatial
Frontal lobes
Voluntary body movement, speaking, thinking, judgment, expression of feelings; prefrontal cortex = regulation/adaptation of emotions, morality, social cognition, decision-making
Parietal lobes
Perception/interpretation of sensory info (touch, pain, taste, body position); language interpretation tied to LEFT parietal lobe
Temporal lobes
Hearing, short-term memory, sense of smell; emotion expression via limbic connection; LEFT temporal lobe (+ left parietal) = language interpretation
Occipital lobes
Visual reception & interpretation
Diencephalon (Thalamus + Hypothalamus)
Connects cerebrum to lower brain structures
Thalamus
Integrates ALL sensory input except smell; blocks minor sensations to allow focus (e.g., ignoring a ticking clock while studying); dopamine effects here linked to neuropsychiatric disorders
Hypothalamus
Regulates pituitary gland (releasing factors), ANS, appetite/temperature/thirst, blood pressure, circadian rhythms (via suprachiasmatic nucleus)
Midbrain (mesencephalon)
Visual, auditory, and righting (balance) reflexes
Pons
Relay station; connects cerebellum/brainstem; cranial nerves V–VIII; respiration & skeletal muscle tone centers; associated with sleep and dreaming
Medulla
Vital centers: HR, BP, respiration; reflex centers for swallowing, sneezing, coughing, vomiting; cranial nerves IX–XII
Cerebellum
Involuntary movement, coordination, muscle tone, posture/equilibrium
Basal ganglia
4 subcortical nuclei (striatum, pallidum, substantia nigra, subthalamic nuclei) — subconscious voluntary movement (arm swing while walking), muscle tone
Gyri
folds
sulci
grooves — ↑ surface area/neurons of cortex
Brainstem
medulla + pons + midbrain
Amygdala
primary gateway for processing novel/ambiguous emotional stimuli (fear, anxiety, panic)
cell body
contains nucleus, keeps neuron alive
dendrites
transmit impulses TOWARD cell body
axon
transmits impulses AWAY from cell body
Myelin
phospholipid sheath (from neuroglia) → insulates, ↑ impulse velocity; white matter = myelinated; gray matter = cell bodies, no myelin
Afferent (sensory)
carry impulses FROM periphery TO CNS
Efferent (motor)
carry impulses FROM CNS TO effectors (muscles/glands)
Interneurons
entirely within CNS; 99% of all nerve cells; responsible for thinking, feelings, learning, language, memory
Synapse
junction between 2 neurons
Synaptic cleft
space between axon terminal & next neuron
Presynaptic neuron
conducts impulse toward synapse
Postsynaptic neuron
conducts impulse away
Reuptake
NT is stored for reuse — key mechanism target of many psychotropic drugs
Sympathetic
dominant during stress; fight-or-flight; originates thoracolumbar spinal cord; ↑ HR/RR, ↓ digestive secretions/peristalsis, blood shunted to vital organs/muscles
Parasympathetic
dominant when relaxed; originates brainstem + sacral spinal cord; normal HR/RR, ↑ secretions/peristalsis (digestion), promotes elimination
Acetylcholine (cholinergic)
Sleep, arousal, pain, movement, memory
Norepinephrine (monoamine)
Mood, cognition, perception, cardiovascular, sleep-wake
Dopamine (monoamine)
Movement/coordination, emotions, reward, judgment, ↓ prolactin release
Serotonin (monoamine)
Sleep/arousal, libido, appetite, mood, aggression, pain
Histamine (monoamine)
Wakefulness, pain, inflammatory response
GABA (inhibitory amino acid)
Slows body activity, ↓ neuron activity
Glycine (inhibitory amino acid)
Recurrent inhibition of motor neurons
Glutamate/Aspartate (excitatory)
Relay sensory info, motor/spinal reflexes
D-Serine (excitatory)
Co-agonist at NMDA receptor
Endorphins/enkephalins (neuropeptide)
Pain/peristalsis modulation
Substance P (neuropeptide)
Pain regulation
Somatostatin (neuropeptide)
Stimulates/inhibits multiple NTs depending on brain region
Acetylcholinesterase
enzyme that inactivates acetylcholine
MAO and COMT
inactivating enzymes for norepinephrine and dopamine
MAO
inactivating enzyme for serotonin and histamine