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Mendel’s Laws
Principle of Independent Assortment and Principle of segregation
what is the principle of dependent assortment
inheritance of one trait has no effect on the inheritance of another trait, genes for different traits assort independently of one another in gamete production
what is the principle of segregation?
2 members of a gene pair segregate from each other in formation of gametes, half of the gametes carry one allele and the other half carry the other allele. Each gene has 2 copies(alleles) and a parent will give one copy to a child, the other parent will give one-thus giving 2
what is genetics?
the study of structure, composition, and function of genes. a science which deals with the principles of heredity and variation
what is heredity
those traits or characteristics which are transmitted from generation to generation, can be physical, eye color, blood type, disease.
what is the chromosome? structure of chromosome?
strands of DNA (genetic material for all living organisms) located in cell nucleus, genes in linear order(not numerical), characteristic number fixed with species, originate in pairs.
what are the different types of chromosomes
autosomes, sex chromosomes
what are autosomes
chromosomes other than sex chromosomes
what are sex chromosomes
carry material to determine secondary sex characteristics/ gamete production
sex chromosomes in mammals
x chromosome and y chromosome
what are females? (sex chrom)
homogametic XX
what are males? (sex chrom.)
XY heterogametic
how do sex chromosomes in mammals work?
all normal egg cells carry one X and ½ normal sperm cells carry one X and the other ½ normal sperm cells carry one Y
diversity of sex determination
the sexual differentiation triggered by a main gene (a sex locus) with a multitude of other genes following in domino effect
sex determination systems?
z/w system (females are heterogametic, males homogametic; birds, reptiles, etc) x-0 system (females have 2 copies of sex chromosome (xx) but males only have one(x0) sex is determined by number of genes expressed across 2 chromosomes) haplo-diploid system(females are diploid and developed from fertilized eggs, 2 sets of chromosomes, males are haploid and develop from unfertilized egg, one set
what are alleles
a variant of a gene controlling the same trait, 2 forms of alleles exist: dominant allele and recessive allele
relationship with dominant and recessive
dominant will always express over recessive. dominant: capital letters, recessive lower case
dominant
will always be displayed even in a heterozygous with recessive allele, complete dominance
recessive
only shown in homozygous
homozygous
condition which both members of allele pair are indetical
heterozygous
allele pair are NOT identical
genotype
genetic makeup of an organism
phenotype
physical features/appearance of organism: expression of genotype, not only produced by genotype but also interaction between genotype and environmental factors
codominance
both alleles are expressed in phenotype when present in heterozygous state, roan both are seen
incomplete dominance
condition in the heterozygote where both genes are expressed in a way that differs from either homozygous condition, mixed, pink rose
what is a punnett square
a tool that allows you to see different gene combinations that are possible when two parents have offspring
what is hybridization
process of crossing two genetically different individuals
what is a hybrid
the progeny(offspring) of hybridization ex: coyote dog, puma
types of hybrids
monohybrid, dihybrid
what is a monohybrid
an organism which is heterozygous with respect to only ONE pair of allele at a locus under study
what is a dihybrid
an organism which is heterozygous with respect to TWO pairs of alleles at two loci under study
why might you want to crossbreed?
to take advantage of heterosis/hybrid vigor, to produce animals which blend characteristics of two or more breeds into a more desirable combination not available in any one breed, produce foundation stock for developing new breed
what is a reciprocal cross
two reverse crosses in which the sexes of the parents are interchanged, if the traits are autosomal the reciprocal cross always yields the same, if sex chromosome it gives different results
what is a breeding system?
set of management practices that are used by producers to ensure the transmission of certain traits from parent to offspring
what does a successful breeding systems need to consider? these factors can also affect these plans
environment, economical factors and technology
what to consider when finding what plan is best for you
climate conditions, types of market, knowledge of genetics, size of operation, personal preference, available resources, goals of breeder
what is random mating
individuals are selected for breeding, they may be managed in one breeding group with one or multiple sires, ultimately, there is no action taken to determine which animals from the selected group mate. animals choose who they mate with in group
what is pedigree mating
implies that all individuals in a genetic population are related to some extent
what is inbreeding?
closed herd, closely related breeding which may increase genetic uniformity but reduce performance especially fertility and survival
when to use inbreeding
when wanting to keep offspring pure, used more in purebred operations
what is phenotypic mating
plans are based on performance or visual appearance, not pedigree, and are called assortative
what is assortative mating and difference between positive and negative
breeding where individual with similar traits or genotypes tend to mate with each other. positive pairing is similar phenotypes/genotypes use to mate best to best and negative is pairing dissimilar phenotypes/genotypes use to mate worst to best to correct problems
what is crossing breeding
two different breeds, usually both purebreds, hybrid vigor: superior traits that come from crossbreeding causing offspring to have better traits than parents=heterosis
hybrid vigor
hybrid vigor: superior traits that come from crossbreeding causing offspring to have better traits than parents=heterosis
straight breeding/purebred breeding
registered purebred male crossed with a female of the same breed
what is grading up
mating purebred male (sire) to grade or unregistered or crossbred female (dam) to improve herd
benefits of grading up
improves quality, develops uniformity, increased performance in offspring
what is outcrossing
mating animals within the same breed but having no common ancestors on either side
what is linebreeding?
form of inbreeding to produce offspring with deserved characteristics, one selected parent should have one or more common ancestors in the pedigree in the last 5 generations
negatives of inbreeding
decrease reproductive efficiency, decrease vigor, decrease survivability and physical abnormalities
most important traits for selection
reproductive performance(highest economic value), maternal ability(milk), growth and efficiency(weaning, post weaning), market price, temperament(cattle) flocking instinct(sheep), longevity
what is EPD
expected progeny differences:the prediction of how future progeny of each animal are expected to perform relative to progeny of other animals in the database. expressed in units of measure for the trait, plus or minus(closer to 1,0 indicates higher reliability)
how to select without genetic data
use visual appraisal: structural soundness, breeding soundness, udder capacity, indicators of productivity and adaptability and visible factors affecting market price
what are 2 major phases with development
before birth/hatch(pre-natal) and after birth/hatch(post-natal)
pre-natal
from formation of embryo, through development of fetus to parturition
post-natal
begins immediately after birth
what is the most critical period
first 6 weeks
what are the four essential stages in early animal development
fertilization, cleavage, gastrulation, organogenesis
what do gastrulation and organogenesis contribute to together
morphogenesis-the biological process that results in organism’s shape and body organization
fertilization
the process of single sperm cell combining with single egg cell to form a zygote
cleavage
rapid, multiple rounds of mitotic cell division where the overall size of the embryo does not increase. the developing embryo is called a blastula following completion of cleavage
gastrulation
occurs after implantation, dramatic rearrangement of cells in blastula to create the embryonic tissue layers. these tissue layers will go on to produce the tissues and organs of adult animal
blastula
developing embryo
organogenesis
the process of organ and tissue formation via cell division and differentiation
important outcomes of gastrulation
formation of 3 germ layers,2 formation of embryonic gut(archenteron), 3appearance of major body axes
what are the 3 germ layers
ectoderm, mesoderm, endoderm; process of the tissues and organs that are formed by the developing embryo
ectoderm
gives rise to nervous system the skin epidermis and epithelial lining of mouth and rectum
mesoderm
gives rise to muscle cells and skeletal cells, the circulatory system and reproductive organs
endoderm
gives rise to many internal organs such as liver and pancreas and epithelial lining of digestive and respiratory system
what forms the organs
the continuous development of 3 different germ layers
organogenesis
process of organ and tissue formation via cell division and differentiation
tissue
group of similar cells that work together on specific task
organs
structures made up of two or more tissues organized to carry out a particular function
organ system
group of organs with related functions make up
tissue types
epithelial tissues, connective tissues, muscle tissue, nervous tissue
epithelial tissue
form covering of all body surfaces, their functions include protection, secretion, absorption, excretion, filtration, diffusion and sensory reception
connective tissue
connects and supports other tissues and the function is supporting organs and cells, transporting nutrients and wastes, defending against pathogens, storing fat and repairing damaged tissues
muscle tissues
essential for keeping the body upright, allowing it to move and even pumping blood and pushing food through digestive tract
nervous tissues
involved in sensing stimuli and processing and transmitting info
how does growth occur
hypertrophy(increase in cell size) hyperplasia (increase in cell number, before birth), accretion (a growth or enlargement by gradual build up)
3 tissue types that grow post natal
muscle, bone(matures first), and fat (adipose)
determined growth
mammals, grow to given size(set at birth), growth rate effected by environment
indeterminate growth
fish, lizards, snakes, no predetermined size, unlimited growth, will grow to available nutrients and environment; largely dependent on environmental factors
what makes muscle unique
ability to contract, protein filaments(myosin and actin) and multi-nucleated
what is myogenesis
the process of muscle tissue formation
how do muscles mature
embryonic precursor cells called myoblast fusing to form multinucleated muscle fibers
what determines the number of muscle fibers in an animal
length of gestation(slow pre-natal growth rate=large cell #) small versus large animals (large animal have slow growth at cellular level, rapid growth for live weight gain)
hyperplasia
condition where there is increased number of cells in a tissue or organ, longer gestation = more hyperplasia
what is the humane methods of slaughter act
requires humane treatment and handling of food animals at slaughter plant and providing quick and effective death passed august 27 1958 and was amended 1978 to stop slaughter activities if they believe an animal is being handled inhumanely
why is welfare and handling critical when moving animals
moving animals can be stressful and this should be limited
flight zone
animal’s safety zone which animal will move if human enters this zone
point of balance
imaginary point on animals body(shoulder) where if approached from front or rear, animal will move forward of backward
what is lairage
resting areas in packing plant where animals are contained until slaughter
why is proximity to processing plant important
less time traveling less time in lairage
what is the maximum time animal can be contained
no more than 28 hours
ante-mortem inspection
initial step in detection of any signs of disease, distress, injury of animals when they arrive at plant for slaughter occurs before slaughter. conducted 12-14 before slaughter by qualified vets. examine general behavior, reflexes, fatigue, excitement, gait, posture
ante-mortem inspection letters
u-unfit for slaughter, p-postpone slaughter and treat, s-handle as suspect, d- destroy and dispose, cu-conditionally unfit
immobilization/stunning techniques
mechanical(captive bolt), electrical, chemical (co2), renders animal unconscious and insensible to pain, prepares animal for exsanguination (bleeding)
what is exsanguination
sticking, removal of blood, essential for quality. severing carotid arteries and jugular veins
mechanical stunning
immobilized animals by eliciting trauma to head, captive bolt common in beef