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monism
belief that mind and body are one thing
dualism
belief that mind and body are separate things
neuron
cell specialized for receiving, processing, and transmitting information
cell body (soma)
main part of neuron containing structures to keep the cell alive
nucleus
part of cell containing DNA and controlling cell activities
dendrite
branch-like structure that receives information from other neurons/sensory receptors
axon
long fiber that carries action potentials away from the cell body
axon hillock
area where the axon begins; initiates action potential
axon terminal
end of an axon that communicates with another cell
myelin sheath
fatty covering over many axons that increases neural transmission speed
node of ranvier
small gap between sections of myelin
glial cells
cells that support, nourish, protect, and regulate neurons
blood-brain barrier
protective system that filters what can move through the blood into brain tissue
microglia
glial cells involved in immune defense and cleanup in the nervous system
astrocytes
glial cells that provide support to neurons and help regulate their environment
oligodendrocytes
glial cells that produce myelin in the central nervous system
Schwann cells
glial cells that produce myelin around axons in the peripheral nervous system
membrane potential
difference in electrical charge between the inside and outside of a cell
resting potential
neuron's stable charge when it is not producing an action potential
ion
electrically charged atom or molecule
sodium (Na+)
positively charged ion with a higher concentration outside of the neuron
potassium (K+)
positively charged ion with a higher concentration inside of the neuron
chloride (Cl-)
negatively charged ion important in neural signaling and inhibition
concentration gradient
tendency of particles to move from high concentration to low concentration
electrical gradient
attraction or repulsion of ions based on electrical charge
electrochemical gradient
combined influence of concentration and electrical forces on an ion
selective permeability
cell membrane's ability to allow some substances through more easily than others
sodium-potassium pump
protein that uses energy to move 3 Na+ out and 2 K+ into the neuron, helping maintain the resting potential
depolarization
a change in membrane potential that makes the neuron less negative and generally more likely to fire
hyperpolarization
a change in membrane potential that makes the neuron more negative
threshold
membrane potential that must be reached to trigger an action potential
action potential
rapid electrical impulse that travels down an axon
all-or-none law
principle that an action potential occurs completely or not at all
refractory period
resting period after an action potential when a neuron cannot produce another action potential normally
relative refractory period
period when it is possible to produce another action potential, but it takes a lot of effort
propagation
movement of an action potential along an axon
saltatory conduction
rapid movement of an action potential from node to node along a myelinated axon
local neuron
neuron that communicates primarily through graded changes in membrane potential rather than long-distance action potentials
graded potential
small change in membrane voltage whose size depends on the strength of the input
synapse
junction where one neuron communicates with another
presynaptic neuron
neuron that sends the signal into a synapse
postsynaptic neuron
neuron that receives the signal from a synapse
synaptic cleft
tiny space between the pre- and postsynaptic cells
reflex arc
neural pathway involved in a reflex, including sensory and motor neurons
spontaneous firing rate
rate at which a neuron produces action potentials without a particular external stimulus
EPSP (excitatory postsynaptic potential)
graded potential that makes the postsynaptic neuron more likely to produce an action potential
IPSP (inhibitory postsynaptic potential)
graded potential that makes the postsynaptic neuron less likely to produce an action potential
excitation
neural activity that increases the likelihood of an action potential
inhibition
neural activity that decreases the likelihood of an action potential
temporal summation
combining of multiple signals arriving from the same location at different times
spatial summation
combining of signals arriving from different locations at the same time
summation
process where multiple EPSPs and IPSPs combine to influence a neuron reaching threshold
neurotransmitter
chemical released by a neuron that affects another cell across a synapse
neuromodulator
chemical messenger that produces broader and longer-lasting changes in neural activity
neurotransmitter receptor
protein that recognizes a specific neurotransmitter and responds to it
reuptake
process in which a released neurotransmitter is transported back into the neuron that released it
enzyme
protein that speeds up a chemical reaction
enzymatic breakdown
process of using enzymes to break down a neurotransmitter
diffusion
movement of molecules from high concentration to low concentration
synaptic vesicle
small membrane container that stores neurotransmitters in the axon terminal
exocytosis
process in which a vesicle fuses with the cell membrane and releases neurotransmitter into the synaptic cleft
presynaptic terminal
end of the axon where neurotransmitters are released
ionotropic receptor
receptor that directly opens an ion channel when activated by a neurotransmitter
metabotropic receptor
receptor that works indirectly to open ion channels; takes longer but also lasts longer
glutamate
major excitatory neurotransmitter in the brain
GABA
major inhibitory neurotransmitter in the brain
glycine
important inhibitory neurotransmitter, especially in the spinal cord
dopamine
a monoamine involved in movement, motivation, reward, and other functions
epinephrine
monoamine involved in arousal, attention, and other functions
serotonin
monoamine involved in mood, sleep, appetite, and other functions
endorphins
neuropeptides involved in reducing pain and influencing other behaviors
ATP
purine that can function as a chemical messenger and energy-related molecule
adenosine
purine neuromodulator involved in regulating neural activity
nitric oxide
gas messenger that can affect nearby neurons and blood vessels
endocrine system
system of glands that produce and release hormones
target cells
cells that have receptors for a particular hormone or chemical messenger
endocrine gland
gland that releases hormones into the bloodstream