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when does the portal vein develop?
8th embryonic week
from what part of the primitive gut does the liver form?
foregut
what drains bile from the liver?
bile canaliculus, right/left hepatic ducts
what is bile made of?
water, salts, pigments
homogenous texture
less echogenic than diaphragm, pancreas, spleen
more echogenic than kidney
liver echogenicity
what separates the right and left lobe of the liver?
main lobar fissure, main portal vein
what separates the left lobe and caudate lobe?
ligamentum venosum
what separates the right lobe into anterior and posterior segments?
right intersegmental fissure
what separates the left lobe into medial and lateral segments?
left intersegmental fissure, falciform ligament, ligamentum teres
tongue-like projection of right lobe which elongates it, more common in women
Riedel’s lobe
what covers the liver?
Glisson’s capsuleq
where is the gallbladder in reference to the liver?
posterior, inferior
what are the extrahepatic ducts?
common bile duct, some CHD/cystic duct
what are the intrahepatic ducts?
right posterior and anterior sectoral duct, right/left hepatic duct, common hepatic duct
line sinusoids (vascular spaces between hepatocytes)
break down hemoglobin into bilirubin
conjugate bilirubin
break down old RBCs, bacteria
Kuppfer cells
what is the umbilical vein after birth?
ligamentum teres
separates right and left lobe, contains middle hepatic vein (cephalic) and gallbladder fossa (caudal)
main lobar fissure
inflammation of the gallbladder, often due to gallstones
may necessitate cholecystectomy
cholecystitis
what makes the mickey mouse sign?
common bile duct, hepatic artery, portal vein
moderate to severe increase in AST, ALT
miniminal to moderate increase in alk phos
minimal to severe increase in bilirubin
signs of hepatocellular disease
mild increase in AST, ALT, alk phos
severe increase in bilirubin
signs of obstructive disease
what combines to form the common bile duct?
common hepatic duct, cystic duct
what combines to form the common hepatic duct?
right and left hepatic ducts
what may cause increase in the size of the gallbladder?
age, gallbladder removal