Lab values; O2 transport in blood

Relevant blood tests

-Complete blood count (CBC): hgb,RBC,Hct

Normal Hgb (females)

12-16 g/dL

Normal hgb males

14-17.4 g/dL

Increased Hgb may be _________ or ___________

-pathological or normal

-expected in smokers, high altitude, CHF, polycythemia

Decreased Hgb limits the ___________ and _________ of O2 to tissue

-availability and transport

Effect of pH and temp on Hgb

-less binding in acidic and hotter environments

-more binding in alkaline and cooler environment

RBC normal range female

-3.6-5 cell/ mcL

RBC normal range male

-4.2-5.4 cells/mcL

increases RBC increases

-viscosity of blood

-risk for thrombus formation, stroke, MI

decreased RBC

-reduces O2 carrying capacity

Hematocrit

-Packed RBCs as a percentage of total volume of whole blood

Normal Hct females

-36-48%

Normal Hct males

-42-55%

Increased Hct increases

-viscosity of blood

-risk for thrombus formation, stroke, MI

Decreased Hct

-reduces O2 carrying capacity of blood

MCV

-mean cell volume

-avg vol of RBC

-hct/RBC

McHgb

-avg amt

-(hgb/rbc) x 10

McHc

-mean corpuscular hemoglobin concentration

-(hgb/hct) X100

RDW

-red cell distribution width

-not used frequently