MED ORG LEC - CNS Drugs

Drugs for Parkinsonism

• Levodopa

• Carbidopa

• Amantadine

Levodopa

Carbidopa

Amantadine

Typical/First Generation Antipsychotics

• Phenothiazines

• Thioxanthenes

• Butyrophenones

Typical/First Generation Antipsychotics MOA

Inhibits D2 receptors

Atypical/Second Generation Antipsychotics MOA

Inhibits 5-HT24 & D4 to D2

Chlorpromazine

Thioridazine

Perphenazine

Thioxanthene

Which of the ff. is Not a Phenothiazine:

• Chlorpromazine

• Thiodazine

• Perphenazine

• Thioxanthene

Alipathic Phenothizines

Has the suffix -promazine

Piperidine Phentodiazine

Has the suffix -ridazine

Piperazine Phenothiazine

Has the suffix -phenazine

Butyrophenones

Has the suffix -peridol

• Haloperidol

Haloperidol

Diarylazepines

Has the suffix -apine

• Loxapine

• Clozapine

• Quetiapine

Loxapine

Clozapine

Quetiapine

Imipramine

Amitriptyline

Doxepin

Selective Serotonin Reuptake Inhibitors (SSRIs)

para-halo substitution

• Paroxetine

• S-citalopram

• S-fluoxetine

• Sertraline

• Fluvoxamine

Paroxetine

S-citalopram

S-fluoxetine

Sertraline

Fluvoxamine

MAO Inhibitors (MAOIs)

MPITS

• Moclobemide

• Phenelzine

• Isocarboxazid

• Tranycypromine

Serotonin-2 Antagonists/Reuptake Inhibitors (SARIs)

Suffix -zodone

• Trazodone

• Nefazodone

• Vilazodone

NE-DA Reuptake Inhibitors (NDRIs)

• Bupropion

NE-Specific Serotonergic Antidepressant (NASSA)

• Mirtazapine

Stimulants

• Methylxanthines

  • Caffeine

  • Theophylline

  • Theobromine

Caffeine

Theophylline

Theobromine

Stimulants

• Reuptake Blockers

  • Amphetamine

  • Atomoxetine

  • Modafinil

  • Methylphenidate

  • Sibutramine

  • Phentermine

  • Phenmetrazine

  • Cocaine

Zaleplon

Eszopiclone

Zolpidem

Phenobarbital

• Long-acting

• Anticonvulsant

Thiopental

• Ultra short-acting

• For Induction of Anesthesia

Diazepam

Oxazepam

Alprazdam

Flumazenil

Antidote for overdose of Benzodiazepines

Succinimde

Oxazolidinone

Hydantoin

Trimethadione

Ethosuximide

For absence seizures

Phenytoin

Phenobarbital

Carbamazepine

Valproic Acid

GABA (Gamma-aminobutyric acid)

Gabapentin

1 out of 3 GABA Derivatives

Pregobalin

1 out of 3 GABA Derivatives

Vigabatrin

1 out of 3 GABA Derivatives

Nitrous Oxide

Cyclopropane

Halothane

Methoxyflurane

Propolol

Ketamine

Etomidate

Ester

Ester or Amide?

Amide

Ester or Amide?

Ester

Ester or Amide?

Amide

Ester or Amide?

Amide

Ester or Amide?

Amide

Ester or Amide?

Ester

Ester or Amide?

Amide

Ester or Amide?

Ester

Ester or Amide?

Ester

Ester or Amide?

Amide

Ester or Amide?

Ester

Ester or Amide?