Drug Class Spectrum of Activity

Antistaph penicillins

“Staph Aureus, then Strip.”

First-gen cephs

“Staph Aureus, then Strip.”

Natural penicillins

“Strip Entero fast.”

Aminopenicillins

“Strip Entero.”

AP/BLIs

“Staph Aureus minor. Strip Entero fast. H&M and Eco&Co are Anaerobes.”

Second-gen cephs

“Staph Aureus minor. Strip Entero fast. H&M and Eco&Co are Anaerobes.”

ESP/BLIs

“Staph Aureus minor. Strip Entero fast. H&M, Eco&Co, and Pseudo Aerys are Anaerobes.”

Fourth-gen cephs

“Staph Aureus minor. Strip Entero fast. H&M, Eco&Co, and Pseudo Aerys are Anaerobes.”

Third-gen cephs

“Staph Aureus minor weekly. Strip H&M and Eco&Co. Pseudo Aerys with Taz only.”

Macrolides

“Staph Aureus minor weekly. Strip H&M. It’s quite Atypical.”

Clindamycin

“Staph Aureus. Coagulate negative staph. Strip Anaerobes.”

Tetracyclines

“Staph Aureus. Coagulate negative staph. Strip H&M, Eco&Co, and Atypicals.”

Ciprofloxacin (2nd gen FQs)

“Staph Aureus. Coagulate negative staph and Strip; all weekly. H&M, Eco&Co, and Pseudo Aerys are all Atypicals.”

Levofloxacin, moxifloxacin (3rd gen FQs)

“Staph Aureus. Coagulate negative staph weekly. Strip H&M and Eco&Co. Pseudo Aerys goes with Levi, Anaerobes with Moxxie. It’s quite Atypical.”

TMP/SMX

“Staph Aureus. Coagulate negative staph. Strip weekly with H&M, Eco&Co, and some Atypicals.”

Nitrofurantoin

• Staph saprophyticus

• Enterococcus (UTI-causing)

• E. coli, Klebsiella pneumoniae, Proteus mirabilis