Top 100 Drugs (21 - 30)

clonazepan brand name

Rivotril

clonazepam class

benzodiazepine

clonazepam indication

seizure

clonazepam AEs

CNS: sedation, fatigue, dizzy, psychomotor impairment, muscle weakness, confusion, ataxia, anterograde amnesia

CV: hypotension

resp: respiratory depression (esp when coadmin with other respiratory depressants)

clopidogrel brand name

Plavix

clopidogrel class

antiplatelet agent (thienopyridine)

clopidogrel indication

2* prevention of atherothrombotic events in pts with recent MI/stroke, or who have peripheral arterial disease

Management of ACS

clopidogrel AEs

derm: rash

hematologic: bleeding, bruising, epistaxis

colchicine brand name

Myinfla

colchicine class

anti mitotic

colchicine indication

treatment of acute gout, prophylaxis of recurrent gout attacks, CV risk reduction

colchicine AEs

CNS: fatigue

GI: ab pain, n/v, diarrhea

conjugated estrogens brand name

Premarin, CES

conjugated estrogens class

estrogen

conjugated estrogens indication

menopausal symptoms, atrophic vaginitis, OP, prevention, dyspareunia

conjugated estrogens AEs

CNS: headache, dizzy, nervous

CV: increased BP

GI: nausea, ab pain

GU: BTB/spotting, bloating, breast tenderness

rare but serious: gallstones, possible CV and break cancer risk

cyclobenzaprine brand name

Flexeril

cyclobenzaprine class

skeletal muscle relaxant

cyclobenzaprine indication

muscle spasm

cyclobenzaprine AEs

CNS: drowsy, fatigue, dizzy

GI: dry mouth

GU: urinary retention

denosumab brand name

Prolia, Jubbonti, Xgeva, Wyost

denosumab class

bone metabolism regulator (RANK ligand inhibitor)

denosumab indication

OP (Prolia, Jubbonti)

cancer related skeletal conditions (Xgeva, Wyost)

denosumab Aes

derm: epidermal rxns (eczema, rash, dermatitis)

infection: increased indicidence

MSK: AFF, arthralgia, back pain

osteonecrosis of the jaw reported in trials using high doses in oncology pts; risk similar to bisphosphonates

dexlansoprazole brand name

Dexilant

dexlansoprazole class

PPI

dexlansoprazole indicaiton

GERD, erosive esophagitis

dexlansoprazole AEs

CNS: headache

GI: diarrhea, flatulence, n/v

digoxin brand name

Lanoxin, Toloxin

digoxin class

cardiac glycoside

digoxin indication

HF, rate control in a fib

digoxin AEs

CNS: dizzy, confusion

CV: arrhythmias, bradycardia, AV block

GI: anorexia, n/v, diarrhea

ocular: blurred vision, yellow halo with toxicity

AEs dose dependent and occur at doses higher than those needed for therapeutic effect

diltiazem brand name

Cardizem CD, Tiazac, Tiazac XC

diltiazem class

CCB (non dihydropyridine)

diltiazem indication

HTN, stable angina, rate control in a fib, SVT

diltiazem AEs

CNS: headache, dizzy

CV: hypotension, edema, bradycardia, heart block (use with caution in HF and 2/3rd degree heart block w/o pacemaker)

GI: constipation

may be associated with gingival hyperplasia

domperidone brand name

Motilium

domperidone class

GI motility agent

domperidone indication

upper GI motility disorders, gastroparesis

domperidone AEs

CNS: headache

GI: dry mouth, ab cramps

metabolic: galactorrhea