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Olfaction
detect ordorants dissolved in air
Odorants (volatile molecules)
dissolved in nasal mucus detected by chemoreceptors
info about food, people, danger
distinguish thousands of odors
detected by olfactory receptor cells
Olfactory epithelium
sensory receptor organ
superior region of nasal cavity
Basal cells
continually replace olfactory receptor cells
replacement and sensitivity receptors decline with aging
Olfactory (Bowman) Glands
help form mucus covering olfactory epithelium
Olfactory receptor cells
primary neuron in sensory smell pathway
bipolar structure: single dendrite and unmyelinated axon
detect odorants
Olfactory hairs
cilia projecting from receptor cell dendrite
house chemoreceptors for specific odorants
perceived smell depends on cell stimulated
Olfactory nerves
CN I
bundles of olfactory cell axons
project through skull’s cribriform plate, enter olfactory bulbs
Detecting smells
sniff repeatedly or breath deeply
mucus contains odorant-bind proteins
odorant binds to protein → stimulates receptor cell → cerebral cortex (perceive, id smell) → hypothalamus (visceral reaction to smell) → amygdala (smell recognition, emotional reaction)