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Phospholipids, Glycolipids, Cholesterol: are amphipathic molecules consists of - two hydrocarbon chains (____________)- tails and phosphate group (___________)- head
hydrophobic
hydrophilic
Cell membrane is composed of:
Phospholipids
Cholesterol
Proteins (integral and peripheral)
Glycocalyx
Properties of membrane Lipids:
1. Undergoes lateral diffusion (10-7 to ____ cm2/sec)
Capable of ___________motion (flip-flop
_________ in distribution
______ permeability and fluidity
10-9
transverse
Assymetry
Passive
This type of protein is embedded in lipids; some cross the entire membrane. They act like gates (allow substances into/out cell)
Intrinsic/integral proteins
This type of membrane protein found along the edge of membrane (inside or outside
Extrinsic or peripheral proteins
Peripheral proteins serve as ______ for hormones; entire complex moves into cell.
receptors
These proteins undergo lateral movement (10-9 to 10-11 cm2/sec)
Extrinsic or peripheral proteins
Proteins functions:
Transport of substances into and out of the cell
___________communication
________characteristics - surface proteins eg. MHC Ags
intracellular
antigenic
_________ chains found on surface of cells covalently linked to membrane proteins and Lipids
carbohydrate
________ - extensive cell coat of intestinal brush border
Glycocalyx
Membrane associated functions and properties are function of the Cell coat including:
Cell surface _____
Blood group specific antigen
Receptor site for ____
Receptor for _____
Cell to cell recognition and adhesion
_________________ antigens
charge
viruses
toxins
Transplantation antigens
Fluid portion of the cell is the _______
Everything in a cell except the nucleus is ________- fluids and particulate matters (organelles)
cytosol
cytoplasm
“little organs”; found only inside the eukaryotic cells
organelles
Surrounded by a double membrane
Usually the easiest organelle to see under a microscope
Control center of cell
Nucleus
Nuclear envelop (Nuclear ________)
membrane
These are fine fibrils about 100 A thick. Composed of DNA and proteins (histones and acid proteins)
Chromatin
2 types of chromatin
euchromatin
heterochromatin
Thread-like structures in