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Bipolar Disorder
increase in serotonin → Mania
increase in norepinephrine → inc BP
Bipolar Disorder
restless, irritable, demanding, manipulative, unable to sleep
Restless in bipolar patient
risk for injury directed to others
Unable to sleep in bipolar
provide calm environment
soothing music
warm bath
warm milk
activity for bipolar patient
non competitive:
painting with colors
delivery of linens
First line of medication for Bipolar Disorder
Lithim
Normal value of lithim
0.6-1.2 meq/dl
What to watch out for in taking lithim
L - level: 0.6.1.2
I - increase urination: inc OFI
T - toxicity: corse tremors, kidney damage
H - hand: fine tremors (side effect)
I - increase OFI
U- upset stomach
M - maintain Na level 135 - 145
2nd line of medication for bipolar
Carbamazepine - Tegretol
Carbamazepine - Tegretol WOF
Myelosuppression - increase WBC → risk for infxn
Major Depression
last for 2 weeks
Dysthymia
last 2 years or more
Functional Depression
depression during solitude
Post part um depression
normal if last 30 days. >30 days = post partum psychosis
Seasonal affective disorder
winter fall depression
Anti Depressant
Tricyclic Antidepressant
Serotonin Selective Reuptake Inhibor
MAOI
TCA
“praning and tililing”
-pramine - triptyline
Tofranil, Elavil, Anapranil, Nortriptyline
SSRI
-xamine, -xetine- pram
Prozac (fluoxetine), Zoloft (sertraline), Paxil, Escitalopram
Side effect of SSRI
sexual dysfunction
MAOI
-promine, - phenelzine, - isocarboxazid
parnate, marplan, nardil
What to avoid when taking MAOI?
tyramine rich food:
processed food, aged food → can lead to HTN crisis
Schizophrenia
dopamine imbalance
Positive symptoms of Schizophrenia
-tion - tion
-sion -sion
-nia - nia
-echo -echo
Hallucination, loss of association
Delusion, Illusion
Insomnia, catatonia
Echolalia, echopraxia
Catatonia
waxy flexibility
WOF: circulatory problem
Echolalia
repitition of words
Echopraxia
repitition of action
Negative Symptoms of Schizophrenia
6 As
Anergia - lack of energy
Avolition - lack of motivation
Alogia - inability to speak
Affect is flat
Anhedonia - no pleasure
Asocial - rejecting friends
Antipsychotic Medication
Typical: Old generation
Atypical: New generation
Typical antipsychotic drug
Haloperidol
Chlorpromazine
Atypical antipsychotic medication
“OSCAR”
respiredone (respiredal)
seroquel (quetiapine)
aripriprazole (abilify)
clozapine (clozaril)
olanzepine (zyprexia)
Priority in Depression
Suicide prevention
Suicidal Ideation
“Have you been thinking about suicide?
Suicidal plan
“What is your plan for suicide?”
Serotonin Syndrom
Hyperthermia, muscle rigidity, tremor
ECT
Maintain NPO pre op
Voided pre op
Short-acting anesthetics and muscle relaxants
monitor vital signs, ECG, and airwat
Confusion and short term memory loss is common
SSRI
Fluoxetine
Sertraline
TCA
Nortryptilline
Amitriptylline
MAOI
Phenelzine
Isocarboxazid
Anxiety
Excessive and presistent worry
Signs of Anxiety
Palpitations, agitation, sweating
4 levels of anxiety
Mild, moderate, severe, panic
Mild Anxiety
Able to problem solve
Severe and Panic
priority is safety
stay with the client
dec environmental stimuli
Fast acting anxiolytics
Mild to moderate
Prevent escalation of anxiety
expression of feelings
breathing techniques
assist in problem solving
Management for Anxiety
Identify triggers
relaxation techniques
cognitive behavioral therapy
Fast-acting, short term, acute anxiety
Benzodiazepine
diazepam, midazolam
Long term, long acting, chronic anxiety
SSRI (fluoxetine, sertraline)
Buspirone
Phobia
fear
Exposure therapy
management for phobia
Obssessive compulsive disorder
obssession and compulsion
Obsession
persistent, unwanted thoughts
compulsion
repetitive behaviors
Management for OCD
do not interrupt during ritual, can inc anxiety