HMG-CoA Reductase Inhibitors Pharmacology Review

Vocabulary flashcards covering the pharmacological profile, indications, nursing considerations, and laboratory monitoring for HMG-CoA reductase inhibitors (statins) based on the lecture concept map.

HMG-CoA reductase inhibtors

The drug class commonly referred to as "-statins", which includes Atrovastatin and simvastatin.

Atrovastatin and simvastatin

Generic names for HMG-CoA reductase inhibtors, sold under trade names such as Lipitor and zocor.

Lipitor and zocor

Trade names for the generic statin medications Atrovastatin and simvastatin.

Indications for "-statins"

Lowers total cholestrol & stabilizes plaque.

Mechanism of Action (MOA) for "-statins"

Reduce rate of cholestrol.

Route / Administration for "-statins"

PO (per os / by mouth).

Adverse Effects & Black Box Warnings for "-statins"

Muscle aches and Increased liver enzymes.

Precautions / Contraindications for "-statins"

Liver disease.

Important Labs & Therapeutic Ranges for "-statins"

Cholestrol, Tryglycerides, and LDL + HDL.

Nursing Considerations for "-statins"

Report muscle aches and best take at bedtime.

Statins Concept Map

A visual diagram showing the drug class, generic and trade names, indications, mechanism of action, route, adverse effects, precautions, labs, and nursing considerations for HMG-CoA reductase inhibtors.