lec 7 - embryonic stem cells

what is embryology

study of the origin and development of a single individual

describe the prenatal period

• 38 weeks long from the zygote to birth/baby

• 2 stages

  • embryonic period

    • first 8 weeks

    • where ESC are seen

    • all major organs are in place/body organization is layed out

    • fetus resembles a body

  • fetal period

    • remaining 30 weeks

    • fetus grows in size and complexity

describe how the embryo progresses during the Embryonic period

describe human embryonic SC and their applications

• potency level?

what kind of potency do the cells in the early stages of vertebrate embryo development have?

pluripotency

• need to be captured to become stem cell lines

how do the early stages of embryogenesis compare across different species

early stages of embryogenesis show many similarities across all species

describe the early stages of embryogenesis

what is the mammalian inner cell mass (ICM)/how does it develop?

describe germ cell tumors and what we learned from them

what is the strain 129 mice? how are they used in research?

what are embryonal carcinoma lines? how can they be treated to manipulate differentiation?

how were early mouse embryo cells identified as embryonic stem cells?

describe the experiment that identifies stem cells