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In what three ways is carbon dioxide transported in the blood?
About 90% is converted to bicarbonate, 5% is bound to hemoglobin, and 5% is dissolved in plasma.
What is the chemical reaction for CO₂ transport as bicarbonate?
CO₂ + H₂O ⇌ H₂CO₃ ⇌ HCO₃⁻ + H⁺
What enzyme speeds up the conversion of CO₂ in red blood cells?
Carbonic anhydrase.
What is the chloride shift?
It is the exchange of bicarbonate ions out of the RBC for chloride ions into the RBC.
How does CO₂ loading promote oxygen unloading?
Hydrogen ions from carbonic acid bind to hemoglobin, reducing its affinity for oxygen and promoting oxygen release.