Leaving Groups/Nucleophiles/Bases

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21 Terms

1
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- OH

strong base, strong nucleophile

2
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- OR

strong base, strong nucleophile

3
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NH2

strong base, strong nucleophile

4
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NR2

strong base, strong nucleophile

5
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-F

weak base, strong nucleophile

6
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-Cl

weak base, strong nucleophile

7
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-Br

weak base, strong nucleophile

8
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-I

weak base, strong nucleophile

9
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-SH

weak base, strong nucleophile

10
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ester

weak base, strong nucleophile

11
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Nitriles

weak base, strong nucleophile

12
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Alkyne

weak base, strong nucleophile

13
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OtBu (tert butoxide)

poor nucleophiles, strong bases

14
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LDA

poor nucleophiles, strong bases

15
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DBU

poor nucleophiles, strong bases

16
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DBN

poor nucleophiles, strong bases

17
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H2O

poor nucleophiles, weak bases

18
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CH3OH

poor nucleophiles, weak bases

19
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ROH

poor nucleophiles, weak bases

20
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R-NH2

poor nucleophiles, weak bases

21
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most neutral

poor nucleophiles, weak bases

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