Amines & Amides – Chapter 18

Amines are derivatives of __.

Ammonia

The two classes of nitrogen-containing compounds are and .

Amines and Amides

An amine in which the nitrogen is bonded only to alkyl groups is called __.

Aliphatic amine

An amine that is bonded to one or more aromatic rings is termed __.

Aromatic amine

Amines can be classified as 1°, 2°, or __ based on the number of carbon atoms attached to the nitrogen.

3°

If part of an aliphatic ring, the amine is known as __ aliphatic amine.

Heterocyclic

The suffix for naming amides derived from carboxylic acids is __.

-amide

The boiling points of primary amines __ as chain length increases.

Increase

Amides are not __; they do not accept protons.

Bases

Amines with one to six carbon atoms are __ in water.

Soluble

The structure of an amide is derived from a __ acid.

Carboxylic

Alkaloids are physiologically active compounds produced by __ that contain heterocyclic amines.

Plants

Amines react as __ in water.

Brønsted–Lowry bases

The longest chain containing the amino group is named for the __ group attached to the nitrogen.

Alkyl

The nitrogen atom in a quaternary ammonium salt is bonded to __ carbon groups.

Four

Amides can undergo __ hydrolysis with heat to produce carboxylic acids and ammonium salts.

Acid

In naming amines, if there are two alkyl groups bonded to the nitrogen, the prefix N is used for __, and they are listed alphabetically.

Each

Because of hydrogen bonding, amines have __ boiling points than hydrocarbons, but less than alcohols.

Higher

Hydrogen bonds in amines are weaker than the hydrogen bonds in __ due to the electronegativity of nitrogen.

Alcohols