Lesson 20: Muscular system anatomy

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52 Terms

1
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What special terminology is used for muscle cell organelles?

Plasma membrane: sarcolemma

cytoplasm: sarcoplasm

endoplasmic reticulum: sarcoplasmic reticulum

muscle cells: muscle fibers.

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What are the two main types of muscle tissue based on structure and function?

Striated muscle and smooth muscle.

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Which muscles are classified as striated muscles?

Skeletal muscle and cardiac (heart) muscle.

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What characterizes striated muscles?

high organization of actin and myosin filaments. With vertical striation

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What characterizes smooth muscle compared to striated muscle?

Poor organization of actin and myosin filaments and absence of vertical striations.

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What is the embryological origin of muscle tissue?

Mesoderm.

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Is muscle tissue vascularized and innervated?

Yes, muscle tissue is both vascularized and innervated.

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What are the four special properties of muscle tissue?

Electrical excitability, contractility, extensibility, and elasticity.

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What is electrical excitability in muscle tissue?

The ability to respond to stimuli by generating muscle action potentials.

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What types of stimuli can trigger muscle action potentials?

Autorhythmic electrical signals and chemical stimuli such as neurotransmitters, hormones, and pH changes.

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What is contractility?

The ability of muscle tissue to contract forcefully when stimulated.

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What is extensibility?

The ability of muscle tissue to stretch within limits without being damaged.

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What is elasticity?

The ability of muscle tissue to return to its original length and shape after contraction or extension.

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What is a muscle fiber in skeletal muscle?

A long

cylindrical

multinucleated

cell formed by the fusion of myoblasts.

Associated with bones

<p>A long</p><p>cylindrical</p><p>multinucleated </p><p>cell formed by the fusion of myoblasts.</p><p>Associated with bones</p>
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Where are nuclei located in skeletal muscle fibers?

At the periphery, just beneath the sarcolemma.

<p>At the periphery, just beneath the sarcolemma.</p>
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Can skeletal muscle fibers divide?

No, they grow by hypertrophy, not by mitosis.

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Type of contraction

Short term forceful contractions

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What type of control does skeletal muscle have?

Voluntary control.

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Where are skeletal muscles located?

They are associated with bones.

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What connective tissue layers organize skeletal muscle?

Epimysium, perimysium, and endomysium.

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What is the epimysium?

A dense connective tissue sheath surrounding the entire muscle. Attached through tendons to the muscle

<p>A dense connective tissue sheath surrounding the entire muscle. Attached through tendons to the muscle</p>
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What is the perimysium?

Intermediate Connective tissue surrounding muscle fascicles.

<p>Intermediate Connective tissue surrounding muscle fascicles.</p>
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What is the endomysium?

Reticular connective tissue surrounding individual muscle fibers.

<p>Reticular connective tissue surrounding individual muscle fibers.</p>
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What is the sarcolemma?

The plasma membrane of a muscle fiber.

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What are T-tubules?

Invaginations of the sarcolemma that conduct action potentials into the fiber.

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What is the sarcoplasmic reticulum?

A specialized smooth ER that stores and releases Ca²⁺ for muscle contraction.

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What are myofibrils?

Parallel contractile structures composed of actin and myosin filaments.

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What is a sarcomere?

The repeating functional unit of a myofibril.

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Which filaments form myofibrils?

Thick myosin filaments

Thin actin filaments

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What structures define a sarcomere?

Z lines at each end.

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What is the A band?

The dark band containing thick (myosin) filaments.

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What is the I band?

The light band containing thin (actin) filaments only.

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What is the H zone?

The central region of the A band containing only thick filaments.

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What is the M line?

The region containing proteins that bind thick filaments.

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What theory explains muscle contraction?

The sliding filament theory.

Fine actin filaments slide over thick ones towards the center of the A band, shortening the sarcomere

<p>The sliding filament theory.</p><p>Fine actin filaments slide over thick ones towards the center of the A band, shortening the sarcomere</p>
37
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Characterize satelite cells

Small size, small nuclei,

Share basmemnt membrane with myocytes

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What role do satellite cells play in skeletal muscle?

They enable regeneration by differentiating and fusing with muscle fibers.

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General characteristcs of Cardiac muscle

Long cells with 1-2 nuclei

Ends of the fibers divide into bracnhes, which communicate thorugh intercalary discs at Z disk

40% of cytosol is mitochondra

Wrapped in endomysium, no perimysium and epimysium

<p>Long cells with 1-2 nuclei</p><p>Ends of the fibers divide into bracnhes, which communicate thorugh intercalary discs at Z disk</p><p>40% of cytosol is mitochondra</p><p>Wrapped in endomysium, no perimysium and epimysium</p>
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Control of cardiac muscle

Involuntary and regulated by ANS and hormones

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Type of contraction of cardiac

Contionous and spontaniuos contraction high enerfy consuming

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Components of cardiac muscle?

GAP junction for transmission of AP

Desmosomes and adherence junctions for anchoring myofibrils

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How are the t tubules in cardiac muscle?

Big

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How is the contraction control in cardiac muscles?

Involuntary

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General charcteristics of smooth muscle

Spindle shaped with an elongated nucleus

Endomysium between musce cells

<p>Spindle shaped with an elongated nucleus</p><p>Endomysium between musce cells</p>
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Myoepithelial cells

Surrounding glands

Increase secretion of ducts

<p>Surrounding glands</p><p>Increase secretion of ducts</p>
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Pericytes

Regulate blood flow

<p>Regulate blood flow</p>
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Myofibroblasts

Attracted to damage border and regenerate connective tissue

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T tubules in Smooth muscles

Not existing

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Regenartion of skeletal muscle

Through satelite sells

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Why does smooth muscle regenerate well?

Because it retains the ability to divide.

Mitotic division

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Why is cardiac muscle regeneration minimal?

Because it lacks satellite cells.