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digoxin therapeutic levels
0.8-2 ng/L
>2 is toxic
toxic effects of digoxin more likely to occur in clients with
hypokalemia
hypomagnesemia
hypoxia
hypercalcemia
heart disease
signs of digoxin toxicity
“A Nasty View Has Dangerous Side-effects”
a nasty view = digoxin toxicity causes vision changes (yellow-green halo or blurred vision)
Arrhythmia
Nausea
Vomiting
Headaches
Disorientation
Seizures
droplet precautions
mask within 3-6ft of pt
gloves
gown
flu, pertussis, rubella, mumps, streptococcal pharyngitis, meningococcal meningitis, pna, scarlet fever,
RSV = contact and droplet
can be in same room if same culture and s/s, private room preffered
dedicated equipment
Fans should be removed from a room for a client with droplet or airborne precautions. Fans may propel the transmission of a pathogen
airborne precautions
N95
gloves and gowns
Negative pressure room
surgical mask on pt if must be transported
visitors need to wear PPE and masks
measles (rubeola), TB, varicella, covid, sars, ebola
can be in same room if same culture and s/s
Fans should be removed from a room for a client with droplet or airborne precautions. Fans may propel the transmission of a pathogen
contact precautions
gloves, gown
gloves ane gowns worn by caregivers and visitors
dispose dressing material into nonporous bag
dedicated equipment or disinfect after each use
client leave room only for essential reasons
ex:
c.diff
hep A (A for Anus) if incontinent until 7 days after onset of jaundice
herpes until lesions crust over
MRSA
RSV = contact and droplet
salmonellosis, shigellosis
staph aureus
VRE (vanc. resistant enterococci) until 3 neg cultures from infectious site (1 week apart)
can cohort if have same CULTURE
don and doff order
don (up the body then hands)
hand hygiene
gown
mask must extend below and under chin
eye protection
gloves- cover wrist portion of gown
doff (in alphabetical order)
gloves
goggles/face shield
gown
mask
HH
vancomycin adverse effects
ototoxicity
red man syndrome
thrombophlebitis
thrombocytopenia
allergy
nephrotoxic
vancomycin trough and peak and toxic levels
trough = one hour before next dose / just before 4th dose (5-10mcg)
peak = 2hr after completion of 3rd dose (25-40 mcg)
toxic > 80 mcg/mL
what to monitor for heparin
PTT, aPTT
PTT should be 1.5-2.5 baseline
prolonged PTT → liver damage, vitamin K deficiency, DIC
what to monitor for warfarin
INR, PT
PT: (2-2.5 base)
INR: (2-3.5 base)
meds to avoid when taking lithium
NSAIDS (naproxen) : reduce renal blood flow, can cause lithium levels to rise to toxicity
ACE inhibitors: promote sodium wasting, low sodium can precipitate lithium toxicity
diuretics
diet for CKD and AKI
renal diet CKD
dec protein, inc carbs, vitamins, Ca replacement, dec sodium and phosphate
AKI
oliguric phase: dec protein,inc carbs, restrict K
diuresis phase: dec protein, inc cals, rest. fluids.
phospahte binder names
sevelamer hydrochloride
calcium acetate
aluminum hydroxide
2 month dev milestones
follow object w eyes
able to pick up head on tummy
head side to side
verbal noises/coos
smiles
4 month dev milestones
lower central incisors
rolls over
babbles (copying noises)
begins to like play
holds and reaches for toys
starts to remember faces
6 month dev milestones
scared of strangers
sit up w support
double weight
responds to name
babbles w vowels
looks at self in mirror
8-9 month dev milestones
sits w/o support
crawls
stand by grippng something
pincer grasp
objects from hand to hand
object permanence
10-12 month dev milestones
cruising/walking
walk alone mastered by 12-14m
follows simple commands
put objects in container
say simple words
separation anxiety
order of developmental stage
trust v mistrust 0-1
autonomy vs shame and doubt 2-3
initiative v guilt 4-6
industry v inferiority school age 6-11
identity v role confusion 11-18
by 4 years old child can
speak 4+ words in a sentence and use 4 sentences to tell a story
understand how and why
talk enough for parent to understand most of time
express feelings n ideas
identify colors
group objects by categories (like food)
what age do baby reflexes dissapear?
moro
tonic neck
rooting
palmar
plantar
sucking
moro 3-4m
rooting 3-4m
tonic neck 4m
palmar 5-6m
plantar (babinski) 12m - pos = toes fan ouft
sucking 12m
peaks for diff administration routes
SL: 5-10min after dissolved
IV: 15-30 min after bag finished
IM: 30-60min
SQ: depends on insulin
if get 2 answers in same range (correct) choose higher one (price is right)
The nurse is obtaining vital signs for a client who has acquired immune deficiency syndrome (AIDS). Prior to entering the room, the nurse should do which of the following?
Incorrect
Correct Answer(s): B
A. Wear gloves and a gown.
B. Perform hand hygiene.
C. Review the client’s viral load.
D. Obtain a disposable stethoscope.
right answer
performing hand hygiene before entering roomn
A disposable stethoscope and blood pressure cuff may be useful for a client with contact precautions, but it would not be necessary for a client with AIDS.
Placing the client in a high Fowler’s position may be helpful for comfort, but it is not a priority unless the client is experiencing respiratory distress
foods high in calcium
broccoli
milk
seafood (high in vit D)
s/s hypoglycemia
sleepiness
cold and clammy
pallor
paresthesias
lack coordination
irritability
hunger
palpitations
blurry vision
tachycardia
clozapine
used in treatment resistant schizophrenia
c/i in pt with seizures bc lowers seizure threshold !!! (dont give to pt w DT)
hyponatremia
confusion, lethargy, and stupor as well as seizures and cerebral edema.
Abdominal cramps are another symptom of hyponatremia. Since water follows sodium, there are decreased levels of sodium in the blood and decreased fluid. This creates a fluid volume deficit, decreased urine output, muscle spasms, and abdominal cramping.
Nausea and vomiting are common signs of hyponatremia
2nd generation antipsychotics
quetiapine, cariprazine, and risperidone
bipolar meds
2nd gen AP not 1st gen
lamotrigine
lamotrgine
mood stabilizer
bipolar disorder & anticonvulsant. Lamotrigine is efficacious for both bipolar mania and depression.
titrated slowly because of the risk of the benign rash that may occur.
Lamotrigine is notorious for a client developing a rash. Two rashes may occur with lamotrigine.
One rash is painful, tender, and blistery, affecting the upper trunk and possibly involving the eyes, lips, and mouth. This is suggestive of Steven Johnson's Syndrome (SJS). This type of rash should be reported immediately, and the client should seek emergency care.
A second benign rash (non-tender, has no systemic features) is common and may occur if the client is rapidly titrated upward.
first gen antipsychotics
haloperidol
donezepil
acetylcholinesterase inhibitor
Alzheimer's disease and dementia
major adverse reaction of this medication is bradycardia, which may cause syncope. The nurse should monitor the client's pulse.
may cause hyperlipidemia
rx hypercalcemia
phosphorus
Calcitonin is a thyroid hormone that decreases the plasma calcium level by inhibiting bone resorption and lowering the serum calcium concentration.
Bisphosphonates are intravenous osteoporosis drugs that can quickly lower calcium levels and are often used to treat hypercalcemia due to cancer
abduction
legs separated
hip arthroplasty
keep abduction
abductor pillow
no bending 90º
high seated toilet
all psych drugs cause
low bp and weight changes
usually weight gain
Phenothiazines
first gen AP / typical
all end in -ZINE (thorazine, compazine, promethazine)
dont cure, just reduce s/s
big doses “we only use zines for the zany (cuckoos)
small doses: antiemetics
major tranquilizes
aminoglycosudes are to abx as phenothiazines are to antipsychotics
ap s/e = ABCDEFG
anticho; (dry mouth, urinary retention)
blurry vision
constipo
drowsy
EPS (tremors, parkinsons, shuffling)
Foto sensitivity
aGranulocytosis (low WBC, immunosuppressed) → report s/s pf infection to hcp
nursing teaching for all other s//e: safety teaching. dec risk for injury
what is nursing action presents w s/e ?
educate them
what is nursing action presents w toxic effect
hold drug and notify hcp
deconate or caprate form of medication
sometimes is a med denoted wit letter D (med-D)
LONG ACTING FORM OF DRUG
IM form given for non-compliance
often court ordered
TCAs
most grandfathered into NNSRI category
mood elevators
Elavil (elevates), Trofranil, Aventyl, Desyrel (ALL RHYME)
S/E
Antichol rdp dry mouth
blurred vision
constip
drowsy
euphoria
must take for 2-4 weeks for benefits to start (teach pt this or will complain)
benzodiazapines
anti-anxiety, minor tranquilizers
ZEP in the name
many end in -pam or -lam
Remember zzzzz’s for falling/going to sleep
prototype: valium, induction of anesthetic, muscle relaxant, alcohol
work quickly but don’t take longer than 2-4weeks
zepplin concert has minors on tranquilizers
used as
sz meds
preop induction of anesthesia
muscle relaxants
etoh withdrawal meds
ventilation, to relx and calm pts on vent down
s/e ABCD
Antichol
blurred vision
constipation
drowsiness
give major and minor tranquilizers at same time, why?
major AP take long time to start working
minor AP start working right away
ex: valium and elavil given at same tume, valium d/c once elavil kicks in
monoamine oxidase inhibitors
names of MAOIs rhyme at beginning
MARpln, NARdil, PARnate
s/e
anticholinergic
blurred vision
constipation
drowsiness
AVOID TYRAMINE
avoid salad “BAR” - bananas, avocados, raisins (dried fruit)
grains okay exxcept yeast
no organs liver, kidney, tripe, heart, no preserved meats (smoked, dried, pickled, hot dogs)
dairy, no cheese except mozzerla, cottage cheese (aka no aged cheese)
no etoh, exlixirs, tinctires (iodine/betadine). caffiene, chocolate, licorice, soy sauce
Teach not to take OTC DRugs
lithium
bipolar (treats mania)
s/e: think lithium. 3 Ps of s/e
Peeing (polyuria)
Pooping (diarrhea)
Paresthesia (earliest s/s of e- imbal)
toxic effects
tremors
metallic taste
severe diarrhea
if experiencing. give fluids and notify hcp
#1 rx for lithium pt presenting w peeing n pooping all the times
give pt fluids bc are s/e
MONITOR SODIUM
low sodium makes lithium toxic
high Na makes lithium ineffective
sodium needs to be normal
prozac/fluoxetine
SSRI
s/e ABCDE
e = euphoria
causes insommnia so give before noon if bid give 6am and noon
when changing dose in adolescenrs and YA watch fpr suicide risk. must be recently changed dose and adolecent or young adult
haldol
basically same as thorazil
first gen just like zines
ABCDEFG
E = EPS
G= teach pt to report sore throat and s/s of infection
may develop NMS from tm haldol
seen in eldery and young white schizophrenics
high fever over 102 - is differentiating factor
their dose should be ½ usual adult dose
EPS = s/e
NMS = emergency
Clozaril / Clozapine
atypical AP
DONT CONFUSE ZAP FOR ZEP
doesn’t have A-F s/e
s'/e is aGranulocytosis
worse than in cancer meds, trashes bm
monitor WBC is #1 nursing intervention
geodon/ ziprasidone
black box
do not use in pts w cardiac conditions bc prolongs QT and could cause sudden cardiac arrest
second gen AP ends in -apine
zoloft/setraline
antidepp
can cause insomnia
interacts w following bc not metabolized in liver:
st johns - can cause serotonin syndrome
warfarin - can cause bleeding
s/e = SAD Head
sweating
apprehensive (doom)
dizziness
HA
nurse should anticipate lowering dose of zoloft for pt on st johns or warfarin
rubella (german measles) v pertussis (whooping cough) v measles
rubella (german measles)
fever'
droplet
rash starts at face and spreads
swollen lymph nodes.
joint pain
rx: hydration and antipyretics
dont let pregnanr women around bc can lead to birth defects
measles (rubeola)
virus
airborne
kolpik spots (tiny white spots inside mouth)
conjuctivitis
maculopapular rash at hairline and goes down
fever and runny nose
rx: vitamin A, hydration, antipyretics
pertussis
flu like symptoms runny nose, fever, cough
bacterial
droplet
cx pneumonia
rx: abx
meds taken without food
Penicillin (and derivatives): Best absorbed without food.
Azithromycin (Zithromax): Typically recommended without food to enhance absorption.
Tetracyclines:
Doxycycline and Minocycline: Avoid dairy and antacids as they inhibit absorption.
Fluoroquinolones (e.g., Ciprofloxacin, Levofloxacin):
Take at least 2 hours before or 6 hours after antacids, dairy, or calcium-enriched products.
biphosphonates
w water, stay uprighft to prevent esophageal irritation
levothyroxine
PPIs
iron
avoid calcium and antacids bc dec absorption
can take w foods if causes GI upset
sucraflate
carbidopa-levodopa
meds that can caus SJS
Monitor for Early Symptoms:
Flu-like symptoms (fever, sore throat, malaise) can precede the skin rash.
Rash: Painful, red/purple macules that blister and may peel.
sulfamethoxazole-trimethoprim
levoflaxin
cefs
penicillin
-mycins
allopurinol
nsaids
phenytoin
phenobarbitral
carbamezapine
lamotrigine
isonazid and rifampin
both hepatotoxic (monitor LFTs)
inonazid need to take w B6 bc will deplete
rifampin will stain secretion orange (wear glasses instead of contacts)
emphasize adherance to prevent resistance
. Any drainage exceeding 70 mL would concern the nurse and require investigation for potential hemorrhage
contractions should be no longer than 90 seconds and no closer than 2 min