motion sickness

vitamin/supplement for nausea

ginger

drug tx options for motion sickness

• antihistamines

• anticholinergics

• antiemetics — reserved for pts not responding to antihistamines

anticholinergic commonly used for motion sickness

scopolamine (Transderm Scop)

scopolamine (Transderm Scop) motion sickness application directions

apply 1 patch behind ear at least 4 hours before effect is needed

may use new patch every 3 days as needed

CIs to scopolamine

hypersensitivity to belladonna alkaloids

closed-angle glaucoma

ADRs of scopolamine

• dry mouth

• CNS effects: drowsiness, dizziness, confusion — do NOT drive

• stinging of eyes and pupil dilation: if touching eyes after handling

• withdrawal sx after d/c: diaphoresis, dizziness, fatigue, HA, nausea

what do you need to avoid when wearing scopolamine patch?

alcohol

MRI - remove before

antihistamines used for motion sickness

diphenhydramine (Benadryl)

dimenhydrinate (Dramamine)

meclizine (Dramamine Less Drowsy)

when should oral antihistamines be taken for motion sickness?

30-60 minutes prior to needing effect

when should scopolamine patch be applied?

4 hours prior to needing effect

why should promethazine NOT be used in children?

risk of respiratory depression

dimenhydrinate (Dramamine) and meclizine (Dramamine Less Drowsy) warnings

CNS depression

incr. IOP (glaucoma)