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Male Reproductive System - Hormone Regulation
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Hormones that control reproductive function are secreted by which glands?
Hypothalamus, anterior pituitary and testes.
Hormones from the Hypothalamus, Anterior pituitary and Testes do what?
Initiate and maintain sperm cell production
Regulate the development and maintenance of sex charcteristics
What is the most important male sex hormone?
Testosterone (produced mostly by Interstitial (Leydig) cells)
2 controls of the Hypothalamus
maturation of sperm cells via hormones
dvlpmt of male secondary characteristics via hormones (mainly testosterone)
3 Functions testosterone
stimulates testes and sperm dvlpmt
underlies sex drive
causes secondary sex characteristics
Secondary sex characteristics of testosterone
deep voice
increased hair growth,
thicken bones, vocal cords, skin
enlarge skeletal muscles, larynx
Hypothalamus and (Gonadotropin-Releasing Hormone) GnRH
GnRH stimulates anterior pituitary to produce/secrete LH and FSH
GnRH is a regulatory hormone (affects hormones and structures)
Luteinizing hormone (LH) → testosterone production
stimulates interstitial (leydig) cells to produce/secrte testosterone
called interstitial cell stimulating hormones (ICSH)
Follicle stimulating hormone (FSH) → sperm production
stimulates sertoli cells to secrete andogren-binding protein (ABP)
ABP binds to testosterone keeps it inside seminiferous tubule
stimulates spermatogenesis increasing sperm count

Negative Feedback Loops and Testosterone Regulation
Hypothalamus releases GnRH
GnRH stimulates anterior pituitary to secrete LH
LH stimulates production of testosterone by interstitial cells
increase testosterone lvls inhibits release of GnRH

Negative Feedback Loops and Sperm Regulation
Hypothalamus releases GnRH
GnRH stimulates anterior pituitary to secrete FSH
FSH stimulates sertoli cells to secrete ABP
ABP binds to testosterone, stimulates spermatogenesis → increase sperm count
increase sperm count → sertoli cells secrete inhibin → inhibits FSH and GnRH
FSH and GnRH lvvld drop → sperm production decreases