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what is in the CNS
brain and spinal cord bathed in cerebro-spinal fluid
what is the integration center
in the CNS, takes info in to decide the action and sends action out to PNS
what is the PNS
cranial and spinal nerves that contain sensory and motor fibers
what is the job of the PNS
connect the CNS to muscles, glands, and all sensory receptors and brings into to and from the CNS
afferent division
sensory info arriving to the CNS
efferent division
motor and exiting the CNS
somatic division
an efferent division that is conscious (skeletal muscles, you can control)
autonomic division
an efferent division that is unconscious (glands, smooth muscles, heart that you cannot control)
what does the sensory function do
pick up information and change both inside and outside of the body
what is a change ?
any stimuli that will cause a reaction (temperature, vision, sound, oxygen, sugar)
what are the effectors ?
responsive parts that are outside of the nervous system (what responds)
what are neurons
one single nerve cell, functional unit
what are neuroglial cells ?
accessory cells that support, take care of, and nourish the neuron
nissl bodies
ribosome clusters that give a gray appearance
axon hillock
connects the soma to the axon (part where soma tapers)
perikaryon
region around the nucleus “cytoplams”
neruofibrils
cytoskeleton that extend into dendrites and axon that give the neuron its shape
how can impulses travel ?
dendrite → cell body → axon (can only travel in one direction)
axonal transport (a.k.a axoplasmic flow)
movement of cellular materials through the axon (it has nothing to do with informational signaling, just cellular material)
anterograde axonal transport
away from soma (neurotransmitters, organelles, nutrients)
retrograde axonal transports
toward soma (materials to be recycled and extracellular substances)
where are neurotransmitters made and stored ?
they are made in the soma and stored in vesicles in the synaptic terminal
axoplamsa
cystoplasm of an axon
axolemma
plasma membrane of an axon
PNS neuroglial cells
satellite cells and schwann cells
CNS neuroglial cells
astrocytes, oligodendrocytes, ependymal cells, microglia
astrocytes
found between neurons and blood vessels
supports
metabolism
regulation of ion concentration
repair process
nutrition
guide neurons to targets
form blood brain barrier
what is the blood-brain barrier
determines what from the blood has access to the neurons
oligodendrocytes
form the myelin sheath around the axons in CNS, clean up debris when injured (1 oligodendrocyte can provide myelin to multiple axons at the same time)
microglia
support neurons, phagocytosis, increase in number during injury or disease
ependymal
have microvilli on luminal surface (inner), joined by gap junctions, produce and monitor cerebro-spinal fluid, line ventricles of brain and spinal cord
satellite cells
cover parts of the soma that dont form synapse (to prevent overload of information), assist with the exchange of nutriens, isolate neuron from extraneous or unwanted stimuli
schwann cells
produce myelin in PNS (can only myeelinate a small part of an axon, need multiple to myelinate entire axon), protects contact from bare axons and causing a short circut
unmyelinated axons
appear gray: in PNS many axons are separated by a single schwann cell (not individually wrapping), in CNS no glial cells
myelinated axons
appear white; oligodendrocytes myelinate several axons, schwann cells myelinate parts of one axon
what is myelin
plasma membrane wrapped around the axon
neurilemma
part of shcwann cell that contains the cytoplasm
nodes of ranvier
gaps in the myelin sheath where the action potential originates (jumps from node to node)
how does myelin function ?
increases the rate of action potential because they only have to generate where node of ranvier is
irritability
ability to respond to a stimuli
excitability
ability to transmit an impulse
action potential (AP)
an electrical impulse changing the permeability of a membrane, the signal being carried down the neuron
nerve impulse
AP moving down an axon
how can an impulse travel faster ?
when the axon is myelinated or has a large diameter
examples of neurotransmitters
achetylcholine (Ach), monamines, amino acids, peptides
enzyme that removes the Ach neurotransmitter
achetylcholinesterase (AChE)
how will an outgoing impulse be sent ?
if the net effect is excitatory and at threshold (if negative and postive go from -70 to +30 AP will go)
what is convergence
a single nerve may receive an impulse from 2 or more incoming fibers, all bring in + to allow AP to move down the nerve
divergence
allows impulse to be amplified and travel to different places (when touch something hot)
serial processing
one neuron to another in a series
parallel processsing
processing information from several neurons at once
reverberation
positive feedback continues the activity of the circuit
nuclei
collection of neuron cell bodies with a distinct boundary
center
collection of neuron cell bodies working together
tracts
bundles of axons
ganglia
collection a neuron cell bodies
nerves
bundles of axons
what is gray matter
non-myelinated material
what is white matter
myelinated axons