ptcbe side effects

tetracyclines (minocycline and tetracycline)

photosensitivity, tooth discoloration and weakened enamel

fluoroquinolones (ciprofloxacin, moxifloxacin)

tendon rupture

penicillins (ampicillin, amoxicillin)

heightened allergies

warfarin, heparin

increased bleeding risk

corticosteroids (prednisolone, dexmethasone)

weight gain, increased risk of infection, diabetes mellitus, osteoporosis

beta 2 agonists (albuterol, salmeterol)

tachycardia, palpitations, anxiety tremor

beta blockers (metoprolol, bisprolol, atenolol)

vivid dreams/nightmares, hypoglyemia, cold extremeties, impotence for men (erectile disfunction)

calcium channel blockers (nifedipine, amlodipine, verapamil, diltiazem)

constipations, ankle swelling, gum overgrowth, flushing, palpitations

nitrates

hypotension, flushing, headache, light-headedness

PDE5 inhibitors (sildenafil, tadalafil, vardenafil)

hypotension, headache, flushing, nasal congestion

benzodiazepines (midazolam, diazepam, oxazepam)

drowsiness, sedation, dependence

aspirin

reye syndrome (in children), tinnitus, bronchospasm, GI irritation/risk of bleeding

opioids (tramadol, codeine, morphine, meperidine)

constipation, miosis (pupil is abnormally small), nausea, dizziness, respiratory depression

proton pump inhibitors (omperazole, pantropazole, lansoprazole)

hypomagnesemia, headace, gastroinestinal, disturbances

prostaglandin eye drops (bimtoprost, latanoprost)

blurred vision, conjunctival reddening, permanent eye color change

metronidazole

gastroinestinal upset, hypersenitivity reactions, taste distrubances

metformin

lactic acidosis, GI upset, weight loss, metallic taste

methotrexate

mouth ulers, bone marrow suppression, pulmonary fibrosis

allopurinol

skin rash

SSRI antidepressants (paroxetine, fluoxetine, sertraline, fluvoxamine)

GI upset, weight disturbances, increased risk of bleeding, serotonin syndrome, suicidal ideation, hyponatremia (low sodium)

ACE inhibitors

hyperkalemia (high potassium levels), persistent dry cough, hypotension

spironolactone

hyperkalemia, gynecomastia (male breast tissue becomes enlarged)

loop diuretics (furosemide, bumetanide)

hypotension, hyperkalemia, dehydration, low electrolye state, hearing loss/tinnitus, increasked risk of gout

antipsychotic drugs (olanzapine, haloperidol, chlorpromazine, risperidone, aripiprazole, quetiapine, clozapine)

extrapyramidal effects (movement disorders), sedation, weight gain, lipid abnormailities, increased risk of diabetes, QT interval prolongation (irregular heart rhythm), sexual dysfunction, agranulcytosis (reduce in white blood cells (clozapine))

carbamazepine (antiepileptic drug)

GI upset, dizziness, ataxia (loss in coordination of muscle/movement), hyponatremia (low sodium levels)

cephalosporins (ceftriaxone, ceftazidime, cefoperazone)

GI upset, antibiotic-associated colitis, increased risk of seizures, hypersensitivity reactions

clopidogrel (antiplatelet drug)

increased risk of bleeding, GI upset, thrombocytopenia (low platlet in blood)

H2 receptor antagonists (randitidine)

bowel disturbances, headache, dizziness

H1 receptor antagonists (first generation cyclizine, promethazine)

sedation, dizziness, GI upset

Insulin

hypoglycemia

laxatives (lactulose, senna, bisacodyl)

abdominal pain/cramps, diarrhea, flatulence (gas)

phenazopyridine

orange urine

NSAID (naproxen, ibuprofen, etoricoxib)

increased risk of bleeding, increased risk of CV events, hypersensitivity reactions, fluid retention

Estrogen/Progestogens

irregular bleeding, mood disturbances, venous thromboembolism (blood clots in veins, increased risk or cervical and breast cancer)

oxygen

discomfort from mask use, dry throat

quinine (antimalarial drug)

tinnitus, deafness, cinchonism, hypoglycemia, blindness

statins (simvastatin, atorvastatin, pravastatin)

headache, GI disturbances, myopathies (muscle movement issues), rhabdomyolysis (breakdown of muscle), elevated liver enzymes, increased risk of diabetes

sulfonylureas (gliclazide)

GI upset, hypoglycemia

thiazolidinediones (pioglitazone)

increase risk of bladder cancer, edema (buildup of fluid in body tissues), dizziness, headache, hypoglycemia, bone fractures, anemia

levothyroxine

GI disturbances, palpitations, arrhythmias, tremor, insomnia

trimethoprim (treat bacterial infections)

GI upset, skin rash, hyperkalemia, megaloblastic anemia

valproate (antiepileptic drug)

gastronintestinal disturbances, tremor, behavioral disturbances, hair loss, pancreastitis, thrombocytolpenia (low platelet)

vancomycin

red man syndrome, ototoxivity (hearing organ damage), nephrotoxiticy, thrombophlebitis (blood clots block blood flow in vein), neutropenia

aminoglycosides (gentamicin, amikacin)

ototoxicity, nephrotoxicity

Z-drugs (zopiclone, zolpidem, zaleplon)

daytime sleepiness, rebound insomnia, CNS effects: confusion, GI disturbances, taste disturbances

5-alpha reductase inhibitors (finasteride, dutasteride)

impotence (erectile disfuntion), reduced libido (diminished sex drive), gynecomastia

biophosphates (alendronic acid, pamidronate, zoledronic acid)

esophagitis, hypophosphatemia, osteonecrosis of the jaw (jawbone does not heal properly), atypical femoral fracture